Nature Search

Age-dependent Zap70 expression in thymocytes regulates selection of the neonatal regulatory T cell repertoire

Lo and colleagues report that double-positive thymocytes from neonates express less Zap70 and show reduced Ca^2⁺/NFAT signaling compared to double-positive thymocytes from older thymi. This diminished Ca^2⁺ signaling alters negative selection for self-reactive TCRs, resulting in a cell-intrinsic temporal window for regulatory T versus conventional T cell development in the thymus.

Brian D. Stadinski
Elizabeth A. Mills
Wan-Lin Lo
ResearchOpen Access07 Oct 2025
Nature Immunology

P: 1-14
Multiple freezing–melting pathways of high-density ice through ice XXI phase at room temperature

Multiple freezing–melting pathways of ice VI are found at room temperature, occurring via the ice XXI and ice VII phases. Supercompressed water structurally evolves from high-density water to very-high-density water.

Yun-Hee Lee
Jin Kyun Kim
Geun Woo Lee
ResearchOpen Access10 Oct 2025
Nature Materials

P: 1-8
Gene deletion as the cause of α thalassaemia: Genetic lesion in homozygous α thalassaemia (hydrops fetalis)

J. M. TAYLOR
ANDREE DOZY
D. TODD
Research04 Oct 1974
Nature

Volume: 251, P: 392-393
Separation of the Effects of Gibberellic Acid on Leaf and Stem Growth of Dwarf French Bean

A. W. WHEELER
E. C. HUMPHRIES
Research09 May 1964
Nature

Volume: 202, P: 616
Clinical validation of an AI-based blood testing device for diagnosis and prognosis of acute infection and sepsis

In a prospective study enrolling 1,222 patients from 22 emergency departments, a device using a machine-learning-based signature of blood mRNAs demonstrated clinically acceptable performance to diagnose bacterial and viral infections and to predict the all-cause need for critical care interventions within 7 days, with benchmark to established biomarkers and risk scores.

Oliver Liesenfeld
Sanjay Arora
Nathan I. Shapiro
ResearchOpen Access30 Sept 2025
Nature Medicine

P: 1-11
Localization of an autosomal dominant retinitis pigmentosa gene to chromosome 7q

Siobhán A. Jordan
G. Jane Farrar
Peter Humphries
Research01 May 1993
Nature Genetics

Volume: 4, P: 54-58
Early Data from the Ultraviolet Sky-scan Telescope in the TD1 Satellite

R. WILSON
S. GARDIER
A. BOKSENBERG
Research17 Jul 1972
Nature Physical Science

Volume: 238, P: 34-36
Effects of Quality of Light on Development of Roots on Dwarf Bean Hypocotyls in Presence and Absence of Boron

E. C. HUMPHRIES
Research20 May 1961
Nature

Volume: 190, P: 701-703
Oogenetic Origin of Messenger RNA for Embryonic Synthesis of Microtubule Proteins

R. A. RAFF
H. V. COLOT
P. R. GROSS
Research28 Jan 1972
Nature

Volume: 235, P: 211-214
Gene deletion as the cause of α thalassaemia: The severe form of α thalassaemia is caused by a haemoglobin gene deletion

SERGIO OTTOLENGHI
W. GEORGE LANYON
WONG HOCK BOON
Research04 Oct 1974
Nature

Volume: 251, P: 389-392
A molecular genetic service for diagnosing individuals with familial hypercholesterolaemia (FH) in the United Kingdom

Karen E Heath
Steve E Humphries
Maureen Boxer
Research20 Apr 2001
European Journal of Human Genetics

Volume: 9, P: 244-252
Natural Plant Growth Regulators

E. C. HUMPHRIES
Books & Arts26 Dec 1964
Nature

Volume: 204, P: 1240
Plant Growth Response in an Electrokinetic Field

L. E. MURR
Research01 Sept 1965
Nature

Volume: 207, P: 1177-1178
The role of molecular genetics in the prenatal diagnosis of retinal dystrophies

K Evans
C Y Gregory
S S Bhattacharya
Research01 Jan 1995
Eye

Volume: 9, P: 24-28
Cæsium-136 in Rain and in Milk

A. MORGAN
J. RUNDO
V. M. EMELEUS
Research24 Mar 1962
Nature

Volume: 193, P: 1150-1151
Latex gloves not enough to exclude viruses

SUSAN G. ARNOLD
JAMES E. WHITMAN JR
MICHELE H. COTTLER-FOX
Research01 Sept 1988
Nature

Volume: 335, P: 19
Effect of Gibberellic Acid and Kinetin on Growth of the Primary Leaf of Dwarf Bean (Phaseolus vulgaris)

E. C. HUMPHRIES
Research12 Apr 1958
Nature

Volume: 181, P: 1081-1082
Interaction of CCC and Water Deficit on Wheat Yield

E. C. HUMPHRIES
P. J. WELBANK
E. D. WILLIAMS
Research01 Aug 1967
Nature

Volume: 215, P: 782
Large rain drops in the bright band

Edward E. Altshuler
Research04 Dec 1980
Nature

Volume: 288, P: 464-465
Evolutionarily conserved role of telomerase reverse transcriptase in programming the microenvironment via regulation of the cGAS–STING pathway

Akincilar, Fidan et al. report a conserved role for telomerase reverse transcriptase in regulating inflammation via the cGAS–STING nucleic acid-sensing pathway in myeloid cells, independent of its telomerase activity.

Semih Can Akincilar
Kerem Fidan
Vinay Tergaonkar
Research06 Aug 2025
Nature Cell Biology

Volume: 27, P: 1342-1356
Observations on the transcriptional activity of the glutathione S-transferase π gene in human haematological malignancies and in the peripheral leucocytes of cancer patients under chemotherapy

S McQuaid
S McCann
P Humphries
Research01 Apr 1989
British Journal of Cancer

Volume: 59, P: 540-543
Histone genes are clustered with a 15-kilobase repeat in the chicken genome

R. J. Crawford
P. Krieg
J. R. E. Wells
Research01 May 1979
Nature

Volume: 279, P: 132-136
Prolonged Whole-Brain Refrigeration With Electrical and Metabolic Recovery

ROBERT J. WHITE
MAURICE S. ALBIN
GEORGE E. LOCKE
Research26 Mar 1966
Nature

Volume: 209, P: 1320-1322
The Molecular Genetics of Pediatric Lipid Disorders: Recent Progress and Future Research Directions

Steve E Humphries
France Mailly
Philippa Talmud
Research01 Oct 1993
Pediatric Research

Volume: 34, P: 403-415
Isolation of cDNA clones encoding T cell-specific membrane-associated proteins

Stephen M. Hedrick
David I. Cohen
Mark M. Davis
Research08 Mar 1984
Nature

Volume: 308, P: 149-153
Inhibition of the Absorption of Dietary Radiostrontium by Aluminium Phosphate Gel and Sodium Alginate in the Rat

T. E. F. CARR
J. NOLAN
Research03 Aug 1968
Nature

Volume: 219, P: 500-501
Dynamo model of double radio sources

R. V. E. Lovelace
Research19 Aug 1976
Nature

Volume: 262, P: 649-652
Effect of Giberellic Acid on Leaf Form

E. NJOKU
Research18 Oct 1958
Nature

Volume: 182, P: 1097-1098
The gene responsible for familial hypocalciuric hypercalcemia maps to chromosome 3q in four unrelated families

Yah-Huei Wu Chou
Edward M. Brown
Christine E. Seidman
Research01 Jul 1992
Nature Genetics

Volume: 1, P: 295-300
Kerr Constants of the Hydrogen Halide Gases

C. H. DOUGLAS CLARK
E. C. HUMPHRIES
Research08 Aug 1936
Nature

Volume: 138, P: 248
Persistent parainfluenza virus shedding during isolation at the South Pole

Harold G. Muchmore
Alan J. Parkinson
John A. R. Miles
Research15 Jan 1981
Nature

Volume: 289, P: 187-189
Structure of Rhombohedral 2 Zinc Insulin Crystals

M. J. ADAMS
T. L. BLUNDELL
S. SHEAT
Research01 Nov 1969
Nature

Volume: 224, P: 491-495
Missing links: Weber–Cockayne keratin mutations implicate the L12 linker domain in effective cytoskeleton function

E.L. Rugg
S.M. Morley
E.B. Lane
Research01 Nov 1993
Nature Genetics

Volume: 5, P: 294-300
Antiviral Effect of Daunomycin

A. COHEN
E. H. HARLEY
K. R. REES
Research05 Apr 1969
Nature

Volume: 222, P: 36-38
A point mutation in the ^Aγ-globin gene promoter in Greek hereditary persistence of fetal haemoglobin

Francis S. Collins
James E. Metherall
Bernard G. Forget
Research24 Jan 1985
Nature

Volume: 313, P: 325-326
Cacao Tannin

E. C. HUMPHRIES
Research13 Nov 1943
Nature

Volume: 152, P: 569
Globin RNA sequences in human leukaemic peripheral blood

A. M. GIANNI
R. DALLA FAVERA
S. OTTOLENGHI
Research10 Aug 1978
Nature

Volume: 274, P: 610-612
Measurement of Thermal Accommodation of Gases on Heated Solids

L. G. CARPENTER
D. E. HUMPHRIES
W. N. MAIR
Research13 Jul 1963
Nature

Volume: 199, P: 164-165
Biological enhancement of cloud droplet concentrations observed off East Antarctica

Marc D. Mallet
Branka Miljevic
Alastair Williams
ResearchOpen Access20 Mar 2025
npj Climate and Atmospheric Science

Volume: 8, P: 1-7
Substrate stiffness regulates triple-negative breast cancer signaling through CXCR4 receptor dynamics

Kenneth K. Y. Ho
Johanna M. Buschhaus
Gary D. Luker
ResearchOpen Access13 Aug 2025
Scientific Reports

Volume: 15, P: 1-14
Retinopathy induced in mice by targeted disruption of the rhodopsin gene

Marian M. Humphries
Derrick Rancourt
Peter Humphries
Research01 Feb 1997
Nature Genetics

Volume: 15, P: 216-219
Sequence of chicken ovalbumin mRNA

L. McReynolds
B. W. O'Malley
G. G. Brownlee
Research29 Jun 1978
Nature

Volume: 273, P: 723-728
Bulbil Formation in Sedum telephium

E. C. HUMPHRIES
J. M. THURSTON
Research09 May 1959
Nature

Volume: 183, P: 1343-1344
High Resolution of Human Plasma Components by Starch Gel Electrophoresis

J. M. FINE
J. LOEB
E. WASZCZENKO-Z
Research16 Aug 1958
Nature

Volume: 182, P: 452-453
Host phylogeny shapes viral transmission networks in an island ecosystem

Sampling the viromes of vertebrates, arthropods and plants on an island ecosystem shows that viral transmission between species is strongly affected by phylogeny but less affected by predator–prey relationships and that generalist viruses pose the greatest zoonotic risk.

Rebecca K. French
Sandra H. Anderson
Edward C. Holmes
ResearchOpen Access07 Sept 2023
Nature Ecology & Evolution

Volume: 7, P: 1834-1843
Structure of Flavoglaucin and Auroglaucin

A. QUILICO
L. PANIZZI
E. MUGNAINI
Research02 Jul 1949
Nature

Volume: 164, P: 26-27
Point mutations of rhodopsin gene found in Japanese families with autosomal dominant retinitis pigmentosa (ADRP)

Keiko Fujiki
Yoshihiro Hotta
Atsushi Kanai
Research01 Jun 1992
Japanese journal of human genetics

Volume: 37, P: 125-132
MOGONET integrates multi-omics data using graph convolutional networks allowing patient classification and biomarker identification

Our understanding of human disease can be improved by integrating the abundance of high throughput biomedical data. Here, the authors use deep learning methods successfully used on images to integrate various types of omics data to improve patient classification and identify disease biomarkers.

Tongxin Wang
Wei Shao
Kun Huang
ResearchOpen Access08 Jun 2021
Nature Communications

Volume: 12, P: 1-13
N-terminal sequences of secretory piece and of α chains of different allotype in rabbit secretory IgA

ALAN P. JOHNSTONE
LAWRENCE E. MOLE
Research24 Jul 1975
Nature

Volume: 256, P: 339-340
Low energy γ-ray observation of NGC4151

G. DI COCCO
G. BOELLA
D. RAMSDEN
Research24 Nov 1977
Nature

Volume: 270, P: 319-320

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