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Showing 1–6 of 6 results
Advanced filters: Author: Edward H Nieh Clear advanced filters

  • Little is known about the mechanisms underlying the orchestration of competing motivational drives. During the simultaneous presentation of cues associated with shock or sucrose, when rats may engage in fear- or reward-related behaviors, amygdala neurons projecting to prefrontal cortex more accurately predict behavioral output and bias animals toward fear-related behavior.

    • Anthony Burgos-Robles
    • Eyal Y Kimchi
    • Kay M Tye
    Research
    Nature Neuroscience
    Volume: 20, P: 824-835

  • Volitional reward taking emerges through a sequence of preluding events. Yet, the underlying neural mechanism is not fully understood. Here authors show a series of temporal dynamics of nucleus accumbens neurons that may substantiate such preluding events to commit “free-willed” animals to reward taking.

    • Terra A. Schall
    • King-Lun Li
    • Yan Dong
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-15

  • The hippocampus geometrically represents both physical location and abstract variables on a neural manifold in mice performing a decision-making task in virtual reality.

    • Edward H. Nieh
    • Manuel Schottdorf
    • David W. Tank
    Research
    Nature
    Volume: 595, P: 80-84

  • Exome sequencing has found an excess of de novo mutations in the ∼4,000 most intolerant genes in patients with two classical epileptic encephalopathies (infantile spasms and Lennox–Gastaut syndrome); among them are multiple de novo mutations in GABRB3 and ALG13.

    • Andrew S. Allen
    • Samuel F. Berkovic
    • Melodie R. Winawer
    Research
    Nature
    Volume: 501, P: 217-221