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Showing 1–8 of 8 results
Advanced filters: Author: Eftychios A Pnevmatikakis Clear advanced filters
  • An optimal model-experiment integration for testing many complex hypotheses is still lacking. Here authors introduce improv, a modular software platform enabling real-time adaptive neuroscience experiments, orchestrating parallel data collection, modeling, and experimental control. Authors demonstrate various use cases, including online neural analysis and closed-loop optogenetics in zebrafish.

    • Anne Draelos
    • Matthew D. Loring
    • Eva A. Naumann
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-14
  • Pacheco et al. present new methods for the unbiased recording and cataloging of sensory activity throughout the Drosophila brain and across trials and individuals. They find auditory activity is temporally diverse but present in neurons throughout nearly all central brain regions.

    • Diego A. Pacheco
    • Stephan Y. Thiberge
    • Mala Murthy
    Research
    Nature Neuroscience
    Volume: 24, P: 93-104
  • Granule cells constitute half of the cells in the brain, yet their activity during behavior is largely uncharacterized. The authors report that granule cells encode multisensory representations that evolve with learning into a predictive motor signal. This activity may help the cerebellum implement a forward model for action.

    • Andrea Giovannucci
    • Aleksandra Badura
    • Samuel S-H Wang
    Research
    Nature Neuroscience
    Volume: 20, P: 727-734
  • To investigate the sensory contributions of barrel cortex, the authors estimate spatiotemporal receptive fields by reverse correlation of multi-whisker stimulation to synaptic inputs. Complex stimuli revealed dramatically sharpened receptive fields, largely due to adaptation, and suggest the potential importance of surround facilitation through adaptation for discriminating complex shapes and textures during natural sensing.

    • Alejandro Ramirez
    • Eftychios A Pnevmatikakis
    • Randy M Bruno
    Research
    Nature Neuroscience
    Volume: 17, P: 866-875