Nature Search

Substrate-bound outward-open structure of a Na⁺-coupled sialic acid symporter reveals a new Na⁺ site

Sialic acid transporters (SiaT) are required for sialic acid uptake in a number of human pathogens and are of interest as targets for antimicrobial drug development. Here the authors present the substrate bound SiaT structure from the uropathogen Proteus mirabilis and provide insights into the mechanism of sialic acid transport.

Weixiao Y. Wahlgren
Elin Dunevall
Rosmarie Friemann
ResearchOpen Access01 May 2018
Nature Communications

Volume: 9, P: 1-14
Structural mechanism of signal transduction in a phytochrome histidine kinase

In this study, authors have solved cryo-EM structures of a bacteriophytochrome in its dark-adapted and illuminated states. The structures reveal the structural mechanism for photoactivation of the phytochrome.

Weixiao Yuan Wahlgren
Elin Claesson
Sebastian Westenhoff
ResearchOpen Access12 Dec 2022
Nature Communications

Volume: 13, P: 1-8
Ultrafast structural changes within a photosynthetic reaction centre

Time-resolved serial femtosecond crystallography is used to reveal the structural changes that stabilize the charge-separation steps of electron-transfer reactions in the photosynthetic reaction centre of Blastochloris viridis on a timescale of picoseconds.

Robert Dods
Petra Båth
Richard Neutze
Research02 Dec 2020
Nature

Volume: 589, P: 310-314
Towards a method for forecasting earthquakes in Iceland using changes in groundwater chemistry

An analysis of groundwater chemistry in northern Iceland from 2014 to 2023 shows that groundwater chemical changes can precede earthquakes by several months and may carry some potential for forecasting earthquakes.

Alasdair Skelton
Erik Sturkell
Ingrid Kockum
ResearchOpen Access06 Nov 2024
Communications Earth & Environment

Volume: 5, P: 1-8
The room temperature crystal structure of a bacterial phytochrome determined by serial femtosecond crystallography

Petra Edlund
Heikki Takala
Sebastian Westenhoff
ResearchOpen Access19 Oct 2016
Scientific Reports

Volume: 6, P: 1-9

Quick links

Search

Filter By:

Substrate-bound outward-open structure of a Na+-coupled sialic acid symporter reveals a new Na+ site

Structural mechanism of signal transduction in a phytochrome histidine kinase

Ultrafast structural changes within a photosynthetic reaction centre

Towards a method for forecasting earthquakes in Iceland using changes in groundwater chemistry

The room temperature crystal structure of a bacterial phytochrome determined by serial femtosecond crystallography

Search

Quick links

Substrate-bound outward-open structure of a Na⁺-coupled sialic acid symporter reveals a new Na⁺ site