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Advanced filters: Author: Elina Thadhani Clear advanced filters

  • This manuscript describes the structure of an endocannabinoid analog-bound CB1 complex and reveals the structural determinants of ligand efficacy. The activation mechanism, unique to CB1, that is exploited by allosteric modulators is also outlined.

    • Kaavya Krishna Kumar
    • Michael J. Robertson
    • Brian Kobilka
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-11