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Showing 1–2 of 2 results
Advanced filters: Author: Elisabeth Davioud-Charvet Clear advanced filters
  • Steroid units can facilitate membrane permeation and bioavailability in drugs. Here, using a medicinal chemistry program, Krieget al. identify an arylmethylamino steroid that kills Plasmodium parasites, likely through a chelate-based quinone methide mechanism, and has activity against Schistosoma mansoni.

    • Reimar Krieg
    • Esther Jortzik
    • Katja Becker
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-12