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Showing 1–3 of 3 results
Advanced filters: Author: Eliza S. Nieweglowska Clear advanced filters

  • The jumbo phage ΦKZ constructs a proteinaceous nucleus-like compartment around its genome that protects phage DNA from degradation by DNA-targeting immune effectors of the host, including CRISPR–Cas and restriction enzymes.

    • Senén D. Mendoza
    • Eliza S. Nieweglowska
    • Joseph Bondy-Denomy
    Research
    Nature
    Volume: 577, P: 244-248

  • To protect from host attack, numerous jumbo bacteriophages establish a micron-scale, protein-based structure to enclose their replicating DNA. Using cryoEM, the authors show that the 2D crystal enclosing this so-called phage nucleus is an assembly of tetramers linked by flexible loops and tails.

    • Eliza S. Nieweglowska
    • Axel F. Brilot
    • David A. Agard
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-12

  • In this study Fossati et al. demonstrate how co-fractionation mass spectrometry can be applied to systematically investigate pathogen proteome organization and host interactome plasticity upon Jumbophage infection of Pseudomonas aeruginosa.

    • Andrea Fossati
    • Deepto Mozumdar
    • Danielle L. Swaney
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-16