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Showing 1–2 of 2 results
Advanced filters: Author: Elizabeth B. Sobolik Clear advanced filters

  • Monoclonal antibodies hold promise for combating serious respiratory virus infections but viruses may evolve to evade them. Here, using structural analysis, the authors show how human parainfluenza virus adapts to escape a powerful antibody by modulating its cell entry mechanism.

    • Tara C. Marcink
    • Gillian Zipursky
    • Anne Moscona
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-14

  • Measles virus infection causes immunosuppression and it’s unclear whether this can be prevented by antivirals. Here, using a canine distemper virus ferret model, the authors show that measles-like immune amnesia and lethal exacerbated respiratory disease after consecutive respiratory virus infections can be mitigated by oral antiviral therapy initiated at the onset of primary clinical signs.

    • Robert M. Cox
    • Josef D. Wolf
    • Richard K. Plemper
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-16