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Showing 1–6 of 6 results
Advanced filters: Author: Elliot M Frohman Clear advanced filters

  • Uhthoff's phenomena are transient disturbances in neurological functioning that can be triggered by an increase in core body temperature in patients with multiple sclerosis (MS). In this article, Frohman et al. discuss the pathophysiological underpinnings of Uhthoff's phenomena, and highlight the importance of differentiating between these events and true MS exacerbations in the clinic.

    • Teresa C. Frohman
    • Scott L. Davis
    • Elliot M. Frohman
    Reviews
    Nature Reviews Neurology
    Volume: 9, P: 535-540

  • The end of 2015 saw the passing of John F. Kurtzke and Richard T. Johnson, two legends in neurology, and founding fathers of neuroepidemiology, neurovirology and neuroimmunology. Here, we pay tribute to these two giants by discussing their impact on the genesis of these profoundly important disciplines.

    • Eric J. Kildebeck
    • Elliot M. Frohman
    News & Views
    Nature Reviews Neurology
    Volume: 12, P: 256-257

  • Multiple sclerosis is characterized by both demyelination and neurodegeneration. The lack of myelin in the retina makes this an ideal structure in which to visualize the latter process. In this Review, Frohman et al. describe the novel use of retinal imaging technology, and in particular optical coherence tomography (OCT), to model the disease process in multiple sclerosis. They suggest that OCT could ultimately be used to identify strategies aimed at neuroprotection in the CNS.

    • Elliot M Frohman
    • James G Fujimoto
    • Laura J Balcer
    Reviews
    Nature Clinical Practice Neurology
    Volume: 4, P: 664-675

  • Cognitive dysfunction is frequently observed in patients with multiple sclerosis (MS), and can have a substantial impact on daily activities and quality of life. In this Review, Fielding and colleagues discuss how ocular motor measures in patients with MS might be used to characterize disruption to wide-ranging networks that support cognitive function, and to track disease progression and responses to novel therapies in these individuals.

    • Joanne Fielding
    • Meaghan Clough
    • Elliot M. Frohman
    Reviews
    Nature Reviews Neurology
    Volume: 11, P: 637-645

  • This Review by Fletcher and colleagues provides a holistic approach to the evaluation and management of sexual dysfunction in patients with multiple sclerosis. The article incorporates the latest data from the fields of urology, neurology, nursing, social work, and psychology. The authors assert that the best approach includes open communication with patients and multidisciplinary management.

    • Sophie G Fletcher
    • Wanda Castro-Borrero
    • Elliot M Frohman
    Reviews
    Nature Clinical Practice Urology
    Volume: 6, P: 96-107

  • A new study has compared the utility of optical coherence tomography and visual evoked potentials in the diagnosis of optic neuritis—an inflammatory condition that is frequently the presenting symptom of multiple sclerosis. The results indicate that the two techniques can provide complementary information for the diagnosis of this condition.

    • Elliot M. Frohman
    • Laura J. Balcer
    • Peter A. Calabresi
    News & Views
    Nature Reviews Neurology
    Volume: 6, P: 125-126