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Showing 1–2 of 2 results
Advanced filters: Author: Elmira Forouzmand Clear advanced filters

  • Herpes simplex virus-1 (HSV-1) infection disrupts transcription termination (DoTT) of host genes, but underlying mechanisms are unclear. Here, Wang et al. show that the HSV-1 immediate early protein ICP27 induces DoTT through interaction with the mRNA 3’ processing factor CPSF and disruption of the processing complex.

    • Xiuye Wang
    • Thomas Hennig
    • Yongsheng Shi
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-13

  • CHYRON (Cell History Recording by Ordered Insertion) enables DNA recording of cellular states and lineage reconstruction by Cas9-targeted insertions of random nucleotides by terminal deoxynucleotidyl transferase.

    • Theresa B. Loveless
    • Joseph H. Grotts
    • Chang C. Liu
    Research
    Nature Chemical Biology
    Volume: 17, P: 739-747