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Showing 1–6 of 6 results
Advanced filters: Author: Elton P. Hudson Clear advanced filters

  • Developing cyanobacteria as CO2-neutral cell factories relies on the knowledge of the regulation mechanisms for growth and metabolism. Here, the authors develop an inducible CRISPRi gene repression library in Synechocystis sp. PCC 6803 and screens genes potentially affecting growth and L-lactate tolerance and production.

    • Lun Yao
    • Kiyan Shabestary
    • Elton P. Hudson
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-13

  • Glycogen is a major energy reserve in eukaryotes and is synthesised in part by glycogenin (GN) and glycogen synthase (GS). Here, authors describe the structural basis of GS regulation, specifically the mechanism of inactivation by phosphorylation.

    • Laura Marr
    • Dipsikha Biswas
    • Elton Zeqiraj
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-14

  • Synthetic metabolic pathways that circumvent photorespiration can improve crop growth. Now, an efficient photorespiration bypass with a new-to-nature carboxylation step has been engineered and demonstrated in vitro.

    • Markus Janasch
    • Elton P. Hudson
    News & Views
    Nature Catalysis
    Volume: 4, P: 94-95

  • Microbial catalysts must partition incoming substrate between synthesis of biomass and synthesis of a desired product. Two-stage bioprocesses can accommodate this tradeoff to maximize process productivity by temporal separation of growth and production phases. This Review discusses the challenges of maintaining a high metabolic activity during the production phase.

    • Kiyan Shabestary
    • Steffen Klamt
    • Elton P. Hudson
    Reviews
    Nature Reviews Bioengineering
    Volume: 2, P: 1039-1055