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Advanced filters: Author: Ema Stokasimov Clear advanced filters

  • Micronuclei, which are common features of nuclei in cancer cells, can generate heritable sources of transcriptional suppression, a finding that establishes an inherent relationship between chromosomal instability and variation in chromatin state and gene expression.

    • Stamatis Papathanasiou
    • Nikos A. Mynhier
    • David Pellman
    ResearchOpen Access
    Nature
    Volume: 619, P: 184-192

  • DNA damage during chromothripsis is caused by deoxyinosine formation on accumulated RNA–DNA hybrids in micronuclei that are then recognized by N-methyl-purine DNA glycosylase and cleaved by apurinic/apyrimidinic endonuclease.

    • Shangming Tang
    • Ema Stokasimov
    • David Pellman
    Research
    Nature
    Volume: 606, P: 930-936