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Showing 1–10 of 10 results
Advanced filters: Author: Emily Darin Clear advanced filters

  • A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

    • Mari E. K. Niemi
    • Juha Karjalainen
    • Chloe Donohue
    ResearchOpen Access
    Nature
    Volume: 600, P: 472-477

  • Integrated Ocean Discovery Program Expedition 402 drilled two in-situ long mantle sections in the Tyrrhenian Sea, revealing that retention of large quantities of melts at mantle levels delayed the birth of an ocean basin.

    • Alessio Sanfilippo
    • Ashutosh Pandey
    • Nevio Zitellini
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-11

  • Whole-genome sequencing, transcriptome-wide association and fine-mapping analyses in over 7,000 individuals with critical COVID-19 are used to identify 16 independent variants that are associated with severe illness in COVID-19.

    • Athanasios Kousathanas
    • Erola Pairo-Castineira
    • J. Kenneth Baillie
    ResearchOpen Access
    Nature
    Volume: 607, P: 97-103

  • An activator of DNA polymerase γ restores function to disease-causing mutant variants and demonstrates a potential route to treatments for inherited mitochondrial disorders involving POLG mutations.

    • Sebastian Valenzuela
    • Xuefeng Zhu
    • Maria Falkenberg
    ResearchOpen Access
    Nature
    Volume: 642, P: 501-507

  • mRNA-1273, an mRNA vaccine that encodes a stabilized prefusion-state severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein, elicits robust immune responses and protects mice against replication of SARS-CoV-2 in the upper and lower airways.

    • Kizzmekia S. Corbett
    • Darin K. Edwards
    • Barney S. Graham
    Research
    Nature
    Volume: 586, P: 567-571

  • The globally distributed marine tubeworm Hydroides elegans is emerging as a powerful model for studying bacteria-induced metamorphosis, and offers insights into developmental biology, marine ecology and host–microbe interactions.

    • Morgan V. Farrell
    • Emily Darin
    • Nicholas J. Shikuma
    News
    Nature Methods
    Volume: 22, P: 1607-1609

  • Previous studies have shown that both rare pathogenic mutations and common genetic variants contribute to the familial risk of developing colorectal cancer. Here, the authors carry out a two-stage genome-wide association study and identify six new loci associated with colorectal cancer.

    • Fredrick R. Schumacher
    • Stephanie L. Schmit
    • Ulrike Peters
    Research
    Nature Communications
    Volume: 6, P: 1-7

  • This paper reports the discovery of a family of Kuiper belt objects with nearly identical surface properties and orbits as that of 2003 EL61, which is the third-largest Kuiper belt object. The family also appears to be fragments of the ejected ice mantle of 2003 EL61.

    • Michael E. Brown
    • Kristina M. Barkume
    • Emily L. Schaller
    Research
    Nature
    Volume: 446, P: 294-296