Nature Search

Predicting opioid consumption after surgical discharge: a multinational derivation and validation study using a foundation model

Chris Varghese
Luke Peters
Caroline Reinke
ResearchOpen Access26 Aug 2025
npj Digital Medicine

Volume: 8, P: 1-16
Effective drug combinations in breast, colon and pancreatic cancer cells

A survey of potency and efficacy of 2,025 clinically relevant two-drug combinations against 125 molecularly characterized breast, colorectal and pancreatic cancer cell lines identifies rare synergistic effects of anticancer drugs, informing rational combination treatments for specific cancer subtypes.

Patricia Jaaks
Elizabeth A. Coker
Mathew J. Garnett
ResearchOpen Access23 Feb 2022
Nature

Volume: 603, P: 166-173
Organoid cultures recapitulate esophageal adenocarcinoma heterogeneity providing a model for clonality studies and precision therapeutics

Esophageal adenocarcinoma (EAC) has a poor 5-year survival rate and lacks robust preclinical models for use in research. Here, the authors show that newly derived organoids recapitulate the transcriptomic, genetic, and morphological landscape of the primary EAC tumors and provide a platform to test drug sensitivity and study tumor clonality.

Xiaodun Li
Hayley E. Francies
Mathew J. Garnett
ResearchOpen Access30 Jul 2018
Nature Communications

Volume: 9, P: 1-13
Serum metabolome associated with severity of acute traumatic brain injury

Traumatic brain injury is associated with changes to the metabolome. Here the authors show that acute traumatic brain injury has distinctive serum metabolic patterns which may suggest protective changes of systemic lipid metabolism aiming to maintain lipid homeostasis in the brain.

Ilias Thomas
Alex M. Dickens
Tommaso Zoerle
ResearchOpen Access10 May 2022
Nature Communications

Volume: 13, P: 1-15
Publisher Correction: Localized management of non-indigenous animal domesticates in Northwestern China during the Bronze Age

Petra Vaiglova
Rachel E. B. Reid
Xinyi Liu
Amendments and CorrectionsOpen Access26 Aug 2021
Scientific Reports

Volume: 11, P: 1-2
Localized management of non-indigenous animal domesticates in Northwestern China during the Bronze Age

Petra Vaiglova
Rachel E. B. Reid
Xinyi Liu
ResearchOpen Access03 Aug 2021
Scientific Reports

Volume: 11, P: 1-13
TILTomorrow today: dynamic factors predicting changes in intracranial pressure treatment intensity after traumatic brain injury

Shubhayu Bhattacharyay
Florian D. van Leeuwen
Tommaso Zoerle
ResearchOpen Access02 Jan 2025
Scientific Reports

Volume: 15, P: 1-18
Measurement invariance of six language versions of the post-traumatic stress disorder checklist for DSM-5 in civilians after traumatic brain injury

Fabian Bockhop
Marina Zeldovich
Tommaso Zoerle
ResearchOpen Access04 Oct 2022
Scientific Reports

Volume: 12, P: 1-15

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