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The number of individuals in a given space influences animal interactions and network dynamics. Here the authors identify general rules underlying density dependence in animal networks and reveal some fundamental differences between spatial and social dynamics.

A series of early-time, multiwavelength observations of an optical transient, AT2022cmc, indicate that it is a relativistic jet from a tidal disruption event originating from a supermassive black hole.

Merkley and Loewen find that anti-intellectualism (distrust in experts and intellectuals) is linked to COVID-19 (mis)perceptions, compliance with public health directives and information search using survey and experimental data from Canada.

SN 2022qmx, dubbed SN Zwicky, is a rare, gravitationally lensed type Ia supernova, magnified by a factor of 25, discovered by the Zwicky Transient Facility. Follow-up Keck observations reveal four multiple images with unusually small separation.

A stripped-envelope supernova, SN 2022jli, shows 12.4-day periodic undulations during the declining light curve, and narrow Hα emission is detected in late-time spectra with concordant periodic velocity shifts.

A genome-wide association study including over 76,000 individuals with schizophrenia and over 243,000 control individuals identifies common variant associations at 287 genomic loci, and further fine-mapping analyses highlight the importance of genes involved in synaptic processes.

This study used interferometric analysis of synthetic aperture radar images to measure postseismic surface deformation after the 2003 Bam, Iran earthquake and shows reversal of coseismic dilatancy in the shallow fault zone that causes subsidence of the surface. Such deformation spread through a fault zone volume may explain the observed shallow slip deficits for some strike-slip fault ruptures.

An extreme Einstein ring ~10,000 times as bright as the Milky Way in the infrared is studied with VLT/ERIS and ALMA, and the authors find that the lensed galaxy is a starburst with a fast-rotating disk, rather than being driven by a major merger.

Observations of optical flares from AT2022tsd (the ‘Tasmanian Devil’) show that they have durations on the timescale of minutes, occur over a period of months, are highly energetic, are probably nonthermal and have supernova luminosities.

Observations of ¹³CO in the atmosphere of a young, accreting super-Jupiter indicate a ¹³C-rich atmosphere, which is attributed to the accretion of carbon from ices enriched in ¹³C through fractionation.

Emerging SARS-CoV-2 variants of concern were detected early and multiple cases of virus spread not captured by clinical genomic surveillance were identified using high-resolution wastewater and clinical sequencing.

A mouse lymphoma model that shows a similar level of genomic instability generally seen in human cancer has been created. In a comparative genomics approach, recurrent genetic alterations found in this model are used as a filter to identify overlapping alterations in human T-cell acute lymphoblastic lymphomas, including in the FBXW7 and NOTCH genes.

In March 2005 the Sunda megathrust earthquake, with a moment magnitude of 8.6, occurred. Concern was then focused further south on the Mentawai area, where large earthquakes had occurred in 1797 (magnitude 8.8) and 1833 (magnitude 9.0). On 12 September 2007, a magnitude 8.4 earthquake occurred, followed by a magnitude 7.9 earthquake 12 hours later. This paper shows that these earthquakes ruptured only a fraction of the area ruptured in 1833 and conclude that the stress state on the portion of the Sunda megathrust that ruptured in 1797 and 1833 was probably not adequate for the development of a single major large rupture in 2007, meaning that the potential for a large megathrust event in the Mentawai area thus remains high.

Abnormal blood lipid levels are important risk factors for cardiovascular and other various diseases. Here the authors conduct a large-scale multi-ethnic epigenome-wide association study combined with epigenetic (cis-QTL and eQTM) data, and identify CpG-lipid traits associations that are specific to or common across racial/ethnic groups.

The Cancer Genome Atlas consortium reports on their genome-wide characterization of somatic alterations in colorectal cancer; in addition to revealing a remarkably consistent pattern of genomic alteration, with 24 genes being significantly mutated, the study identifies new targets for therapeutic intervention and suggests an important role for MYC-directed transcriptional activation and repression.

Acute lymphoblastic leukaemia is characterized by chromosomal rearrangements. Here, the authors carry out RNA-sequencing on a large cohort of patients and identify recurrent rearrangements of MEF2D, which lead to increased transcriptional activity of the gene, and cellular transformation in vitro.

Faults are generally assumed to be more complicated at the surface than at depth. Analysis of the 2010 El Mayor–Cucapah earthquake, in contrast, reveals that the surface trace is nearly straight but the fault must be highly segmented at depth, thus the characteristics of this earthquake could not have been anticipated from surface geology.

Supershear rupture speed occurred at the devastating 2018 magnitude 7.5 Palu earthquake, Indonesia, according to back-projection of teleseismic data.

How accurate are social scientists in predicting societal change, and what processes underlie their predictions? Grossmann et al. report the findings of two forecasting tournaments. Social scientists’ forecasts were on average no more accurate than those of simple statistical models.

Landslides are damaging natural hazards and can often lead to unexpected casualties and property damage. Here, the authors conduct geodetic and hydrological data analyses of the Slumgullion landslide, Colorado, and quantify the mass movement to find it fits a power-law flow theory and responds to hydroclimatic variability.

A multi-ancestry genome-wide association study of prostate cancer performed in 156,319 cases and 788,443 controls identifies 187 novel risk variants associated with the disease. Genetic risk scores associated with overall risk, and risk of aggressive disease in men of African ancestry.

The Cancer Genome Atlas Network describe their multifaceted analyses of primary breast cancers, shedding light on breast cancer heterogeneity; although only three genes (TP53, PIK3CA and GATA3) are mutated at a frequency greater than 10% across all breast cancers, numerous subtype-associated and novel mutations were identified.

Neoadjuvant pembrolizumab promotes a survival benefit with intratumoral and systemic immune responses in patients with recurrent glioblastoma.

With a comprehensive analysis of sequencing data, DNA copy number, gene expression and DNA methylation in a large number of human glioblastomas, The Cancer Genome Atlas project initiative provides a broad overview of the genes and pathways that are altered in this cancer type.

Genomic and epidemiologic analyses of monkeypox cases stemming from a recent outbreak in the Democratic Republic of the Congo suggest that a new clade I lineage is circulating and that its spread may be linked to sexual transmission.