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Showing 1–4 of 4 results
Advanced filters: Author: Erica Bertozzi Clear advanced filters
  • A nanoscale polymer layer formed by mucins at the surface of tumour cells protects them against immune cell attack. This shield can be circumvented through immune cell engineering, using chimeric antigen receptors to stimulate natural killer and T cells or by tethering glycocalyx-editing enzymes to immune cells.

    • Sangwoo Park
    • Marshall J. Colville
    • Matthew J. Paszek
    Research
    Nature Materials
    Volume: 23, P: 429-438
  • Selective nanofiltration membranes with accurate molecular sieving offer a solution to recover rare metals and other valuable elements from brines but this demands the development of membranes with precise sub-nanometer pores surpassing those available today. Here, the authors report a scalable approach for membrane fabrication in which functionalized macrocycles are seamlessly oriented via supramolecular interactions during the interfacial polycondensation on a polyacrylonitrile support layer.

    • Shanshan Hong
    • Maria Di Vincenzo
    • Suzana P. Nunes
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-9
  • Variably methylated intracisternal A particle (VM-IAP) retrotransposons are stable across the murine lifespan. VM-IAP retrotransposons are unaffected by maternal exposure to the endocrine disruptor bisphenol A, an obesogenic diet or methyl donor supplementation.

    • Tessa M. Bertozzi
    • Jessica L. Becker
    • Anne C. Ferguson-Smith
    Research
    Nature Genetics
    Volume: 53, P: 1233-1242
  • Abnormal folate metabolism in mice results in transgenerational epigenetic inheritance of congenital malformations. Here, the authors provide evidence that defective folate metabolism causes germline epigenetic instability and observe multigenerational misexpression of Hira in embryos, implicating Hira transcript levels as a biomarker of maternal phenotypic inheritance.

    • Georgina E. T. Blake
    • Xiaohui Zhao
    • Erica D. Watson
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-17