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Advanced filters: Author: Erica Depasquale Clear advanced filters

Cellular crosstalk mediated by TGF-β drives epithelial-mesenchymal transition in patient-derived multi-compartment biliary organoids

The study reveals that TGF-β–driven epithelial-mesenchymal transition disrupts bile duct development in biliary atresia. Inhibiting this pathway restores epithelial structure and reduces disease features, highlighting a potential therapeutic target.

Hiroaki Ayabe
Erica A. K. DePasquale
Jorge A. Bezerra
ResearchOpen Access17 Jul 2025
Nature Communications

Volume: 16, P: 1-17
Mitochondrial variant enrichment from high-throughput single-cell RNA sequencing resolves clonal populations

Clonal dynamics are inferred from mitochondrial variants in primary human cells.

Tyler E. Miller
Caleb A. Lareau
Peter van Galen
Research24 Feb 2022
Nature Biotechnology

Volume: 40, P: 1030-1034
Transcriptional profile of pyramidal neurons in chronic schizophrenia reveals lamina-specific dysfunction of neuronal immunity

Xiaojun Wu
Rammohan Shukla
Robert E. McCullumsmith
Research16 Jul 2021
Molecular Psychiatry

Volume: 26, P: 7699-7708
Corticostriatal dysfunction and social interaction deficits in mice lacking the cystine/glutamate antiporter

Eduard Bentea
Agnès Villers
Ann Massie
ResearchOpen Access04 May 2020
Molecular Psychiatry

Volume: 26, P: 4754-4769
Abnormalities of signal transduction networks in chronic schizophrenia

Jennifer L. McGuire
Erica A. Depasquale
Robert E. McCullumsmith
ResearchOpen Access12 Sept 2017
npj Schizophrenia

Volume: 3, P: 1-10

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