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Showing 1–3 of 3 results
Advanced filters: Author: Erica Vander Mause Clear advanced filters

  • CD229 is expressed on the surface of multiple myeloma cells, as well as B and T lymphocytes. Here, the authors engineer CD229-specific CAR T cells and, using patient samples and mouse models, show that treatment with these cells reduces tumour burden and results in limited targeting of T cells.

    • Sabarinath V. Radhakrishnan
    • Tim Luetkens
    • Djordje Atanackovic
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-9

  • Atanackovic and coauthors screen COVID-19 patients for antibodies against 9 different SARS-CoV-2 proteins observing responses against the spike (S) proteins, the receptor-binding domain (RBD), and the nucleocapsid (N) protein which were of the IgG1 and IgG3 subtypes. They also characterised immune responses in these patients and their findings will help to identify the most relevant component of the anti-SARS-CoV-2 humoral immune response as well as assist the design of immunomonitoring methods for anti-COVID-19 vaccines.

    • Djordje Atanackovic
    • Stephanie V. Avila
    • Tim Luetkens
    ResearchOpen Access
    Communications Biology
    Volume: 4, P: 1-12