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TERN-501 monotherapy and combination therapy with TERN-101 in metabolic dysfunction-associated steatohepatitis: the randomized phase 2a DUET trial

In the 12-week, phase 2a DUET study, treatment with TERN-501, a thyroid hormone receptor β agonist, as monotherapy or in combination with TERN-101, a farnesoid X receptor agonist, resulted in dose-dependent reductions in liver fat content as compared to placebo in patients with presumed metabolic dysfunction-associated steatohepatitis.

Mazen Noureddin
Naim Alkhouri
Stephen A. Harrison
ResearchOpen Access11 Jun 2025
Nature Medicine

Volume: 31, P: 2297-2305
Cortical Thickness and Subcortical Gray Matter Volume in Pediatric Anxiety Disorders

Andrea L Gold
Elizabeth R Steuber
Daniel S Pine
Research24 Apr 2017
Neuropsychopharmacology

Volume: 42, P: 2423-2433
A coupled microscopy approach to assess the nano-landscape of weathering

Rebecca A. Lybrand
Jason C. Austin
Odeta Qafoku
ResearchOpen Access29 Mar 2019
Scientific Reports

Volume: 9, P: 1-14

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