In Drosophila, upregulation of genes on the single male X chromosome to match that from the two female Xs depends upon the MSL complex. The structures of complexes of MSL subunits now give insight into how the MOF histone acetyltransferase and MSL3 interact with MSL1, indicating that the latter acts as a scaffold to bring the complex together.
- Jan Kadlec
- Erinc Hallacli
- Asifa Akhtar
