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Advanced filters: Author: Eva Edelson Clear advanced filters

  • Telomerase assembles on a multi-domain RNA scaffold that must adopt a specific structure to function. Here, the authors reveal an alternative RNA conformation in living cells that disrupts telomerase activity, suggesting RNA misfolding may challenge proper telomerase assembly.

    • Nicholas M. Forino
    • Jia Zheng Woo
    • Michael D. Stone
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-15