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Showing 1–5 of 5 results
Advanced filters: Author: Evangelia E. Tsakiridis Clear advanced filters

  • Using metabolic dysfunction-associated steatohepatitis-driven hepatocellular carcinoma mouse models, an ATP citrate lyase inhibitor reduces tumour burden and enhances efficacy of current standards of care.

    • Jaya Gautam
    • Jianhan Wu
    • Gregory R. Steinberg
    ResearchOpen Access
    Nature
    Volume: 645, P: 507-517

  • GDF15 treatment in mice counteracts compensatory reductions in energy expenditure, resulting in greater weight loss and reductions in non-alcoholic fatty liver disease compared to caloric restriction alone.

    • Dongdong Wang
    • Logan K. Townsend
    • Gregory R. Steinberg
    ResearchOpen Access
    Nature
    Volume: 619, P: 143-150

  • Anxiety-like behaviour in mice, as a result of psychological stress, is shown to be mediated by GDF15 release in response to adipose tissue lipolysis.

    • Logan K. Townsend
    • Dongdong Wang
    • Gregory R. Steinberg
    ResearchOpen Access
    Nature Metabolism
    Volume: 7, P: 1004-1017

  • Chlorpyrifos is a widely-used pesticide and a common residue on vegetables and fruits. Here the authors show that at non-neurotoxic doses, chlorpyrifos reduces energy expenditure, by inhibiting diet induced thermogenesis, and promotes obesity and insulin resistance.

    • Bo Wang
    • Evangelia E. Tsakiridis
    • Gregory R. Steinberg
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-12