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Showing 1–2 of 2 results
Advanced filters: Author: Evelyne Ruchti Clear advanced filters

  • Synaptic structures disintegrate and fragment as ageing progresses. Here the authors find that miniature neurotransmission is required to maintain adult motor synapse structures in Drosophila and that increasing miniature events can preserve motor ability during ageing.

    • Soumya Banerjee
    • Samuel Vernon
    • Brian D. McCabe
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-12

  • Tau and the Retromer complex are both linked to Parkinson’s and Alzheimer’s disease. Using Drosophila neurodegeneration models, this study finds that low retromer activity induces a specific increase of a highly toxic truncated form of human Tau.

    • Jamshid Asadzadeh
    • Evelyne Ruchti
    • Brian D. McCabe
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-16