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Showing 1–50 of 74 results

Advanced filters: Author: F Guichard Clear advanced filters

Deposition rate and seasonal variations in precipitation of cosmogenic ¹⁰Be

G. M. Raisbeck
F. Yiou
J. C. Ravel
Research15 Nov 1979
Nature

Volume: 282, P: 279-280
Myristylation of picornavirus capsid protein VP4 and its structural significance

M. Chow
J. F. E. Newman
F. Brown
Research11 Jun 1987
Nature

Volume: 327, P: 482-486
Growth rate of manganese nodule measured with ¹⁰Be and ²⁶Al

F. GUICHARD
J-L. REYSS
Y. YOKOYAMA
Research09 Mar 1978
Nature

Volume: 272, P: 155-156
Tephra from the Minoan eruption of Santorini in sediments of the Black Sea

F. Guichard
S. Carey
M. Arnold
Research17 Jun 1993
Nature

Volume: 363, P: 610-612
Seismic reflection profiles across deep continental crust exposed in the Kapuskasing uplift structure

J. A. Percival
A. G. Green
G. F. West
Research01 Nov 1989
Nature

Volume: 342, P: 416-420
Accelerator mass spectrometry measurement of cosmogenic ²⁶Al in terrestrial and extraterrestrial matter

G. M. Raisbeck
F. Yiou
R. Middleton
Research24 Feb 1983
Nature

Volume: 301, P: 690-692
The A-C linker controls centriole structural integrity and duplication

Bournonville et al. identify key proteins of the centriole’s A-C linker and reveals their essential roles in maintaining centriole structure and enabling duplication during cell division.

Lorène Bournonville
Marine. H. Laporte
Virginie Hamel
ResearchOpen Access24 Jul 2025
Nature Communications

Volume: 16, P: 1-19
Schedule-dependent activity of 5-fluorouracil and irinotecan combination in the treatment of human colorectal cancer: in vitro evidence and a phase I dose-escalating clinical trial

C Barone
M Landriscina
A Cassano
ResearchOpen Access12 Dec 2006
British Journal of Cancer

Volume: 96, P: 21-28
More questions on forest decline

R. SIMONAITIS
K. J. OLSZYNA
J. F. MEAGHER
Research30 Jan 1992
Nature

Volume: 355, P: 402
Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency

Inborn errors of the alternative NF-κB pathway in humans impair the development of AIRE-expressing medullary thymic epithelial cells, thereby underlying the production of autoantibodies against type I IFNs and predisposition to viral diseases

Tom Le Voyer
Audrey V. Parent
Anne Puel
ResearchOpen Access08 Nov 2023
Nature

Volume: 623, P: 803-813
C. elegans SSNA-1 is required for the structural integrity of centrioles and bipolar spindle assembly

Here they identify the C. elegans homolog of Sjogren’s Syndrome Nuclear Antigen 1 as a centriole-stabilizing factor. In the absence of SSNA-1 centrioles assemble normally but are prone to fragmenting in the early embryo leading to multipolar spindle formation and embryonic lethality.

Jason A. Pfister
Lorenzo Agostini
Kevin F. O’Connell
ResearchOpen Access05 Jun 2025
Nature Communications

Volume: 16, P: 1-16
Pro-γ-melanocyte-stimulating hormone cleavage in adrenal gland undergoing compensatory growth

P. J. Lowry
L. Silas
F. E. Estivariz
Research03 Nov 1983
Nature

Volume: 306, P: 70-73
Probable modern analogue of Kuroko-type massive sulphide deposits in the Okinawa Trough back-arc basin

P. Halbach
Ko-ichi Nakamura
N. Blum
Research06 Apr 1989
Nature

Volume: 338, P: 496-499
Solubilisation of angiotensin II receptors in rabbit aortae membranes

MARIE-AUDE DEVYNCK
MARIE-GABRIELLE PERNOLLET
F. MERLIN BUMPUS
Research03 May 1974
Nature

Volume: 249, P: 67-69
Electrical coupling between afferent nerve terminal and intrafusal muscle fibre in the frog muscle spindle

F. ITO
N. KANAMORI
H. KURODA
Research03 May 1974
Nature

Volume: 249, P: 69-71
Glacial–Holocene salinity changes in the Mediterranean Sea: hydrographic and depositional effects

Robert C. Thunell
Douglas F. Williams
Research06 Apr 1989
Nature

Volume: 338, P: 493-496
SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture

Centrioles are formed from a nine-fold symmetric cartwheel structure. Using mutants of the cartwheel protein SAS-6, which alters cartwheel symmetry, Hirono, Gönczy, Steinmetz and colleagues show that the microtubule wall also determines centriole shape.

Manuel Hilbert
Akira Noga
Michel O. Steinmetz
Research21 Mar 2016
Nature Cell Biology

Volume: 18, P: 393-403
Shaping quaternary assemblies of water-soluble non-peptide helical foldamers by sequence manipulation

The self-assembly of short amphiphilic α-helicomimetic foldamers bearing proteinaceous side-chains can be controlled by manipulating the side-chain sequence. This enables the foldamers to be programmed to form either discrete helical bundles containing isolated cavities, or pH-responsive water-filled channels with controllable pore diameters.

Gavin W. Collie
Karolina Pulka-Ziach
Gilles Guichard
Research28 Sept 2015
Nature Chemistry

Volume: 7, P: 871-878
Transient increase in obese gene expression after food intake or insulin administration

Régis Saladin
Piet De Vos
Johan Auwerx
Research12 Oct 1995
Nature

Volume: 377, P: 527-528
Excess ³He and ⁴He in Galapagos submarine hydrothermal waters

W. J. JENKINS
J. M. EDMOND
J. B. CORLISS
Research09 Mar 1978
Nature

Volume: 272, P: 156-158
PD-L1⁺ plasma cells suppress T lymphocyte responses in patients with sepsis and mouse sepsis models

Sepsis induces a period of immunosuppression which can be problematic in the face of subsequent infectious challenge. Here the authors show the presence of PD-L1 expressing regulatory plasma cells that can inhibit T cells in a murine model and in patients with sepsis.

Morgane Gossez
Clara Vigneron
Fabienne Venet
ResearchOpen Access28 Mar 2025
Nature Communications

Volume: 16, P: 1-17
Measurement of the effect of quantum phase slips in a Josephson junction chain

Coulomb interactions can cause a rapid change in the phase of the wavefunction along a very narrow superconducting system. Such a phase slip is now measured in a chain of Josephson junctions.

I. M. Pop
I. Protopopov
W. Guichard
Research13 Jun 2010
Nature Physics

Volume: 6, P: 589-592
Pyridine-based strategies towards nitrogen isotope exchange and multiple isotope incorporation

The rapid access to isotopically labeled organic molecules is a sine qua non condition to support these societally vital areas of research. Here the authors present a solution to access labeled pyridines by a nitrogen isotope exchange reaction based on a Zincke activation strategy.

Minghao Feng
Maylis Norlöff
Davide Audisio
ResearchOpen Access18 Jul 2024
Nature Communications

Volume: 15, P: 1-9
Long-term outcomes of lentiviral gene therapy for the β-hemoglobinopathies: the HGB-205 trial

The final report of the phase 1/2 lentiviral gene therapy trial in severe β-hemoglobinopathies, HGB-205, shows a long-term safety profile and sustained reduction of transfusion requirements in patients with β-thalassemia and of sickle cell crises in patients with sickle cell disease.

Elisa Magrin
Michaela Semeraro
Marina Cavazzana
Research24 Jan 2022
Nature Medicine

Volume: 28, P: 81-88
A death in the life of p53

D. P. Lane
News & Views29 Apr 1993
Nature

Volume: 362, P: 786-787
MT1-MMP directs force-producing proteolytic contacts that drive tumor cell invasion

The mechanism of force production by invadopodia is unclear. Here, the authors show that cell surface MT1-MMP when in contact with collagen, induces Arp2/3 branched actin polymerisation on the concave side of invadopodia, which generates a pushing force along with collagen cleavage by MT1-MMP to invade.

Robin Ferrari
Gaëlle Martin
Philippe Chavrier
ResearchOpen Access25 Oct 2019
Nature Communications

Volume: 10, P: 1-15
C₃-symmetric peptide scaffolds are functional mimetics of trimeric CD40L

Sylvie Fournel
Sébastien Wieckowski
Gilles Guichard
Research06 Nov 2005
Nature Chemical Biology

Volume: 1, P: 377-382
Afternoon rain more likely over drier soils

Analysis of observations on six continents reveals a global preference for afternoon rain to fall on locally drier soils—contrary to the predictions of large-scale climate models, and suggesting that such models may exaggerate the occurrence of droughts.

Christopher M. Taylor
Richard A. M. de Jeu
Wouter A. Dorigo
Research12 Sept 2012
Nature

Volume: 489, P: 423-426
Localization of candidate regions for a novel gene for Kartagener syndrome

Ilse Gutierrez-Roelens
Thierry Sluysmans
Miikka Vikkula
Research26 Apr 2006
European Journal of Human Genetics

Volume: 14, P: 809-815
Inhibition of erythroid differentiation and induction of megakaryocytic differentiation by thrombopoietin are regulated by two different mechanisms in TPO-dependent UT-7/c-mpl and TF-1/c-mpl cell lines

F Goncalves
C Lacout
D Duménil
Research02 Sept 1998
Leukemia

Volume: 12, P: 1355-1366
Skin sensitization by misonidazole: A demonstration of uniform mild hypoxia

F A Stewart
J Denekamp
V S Randhawa
Research01 Jun 1982
British Journal of Cancer

Volume: 45, P: 869-877
Profiling the lymphoid-resident T cell pool reveals modulation by age and microbiota

Non-circulating, tissue-resident T cells have been reported for non-lymphoid organs, but their characterization and regulation in secondary lymphoid organs (SLO) are still lacking. Here the authors show that age and microbiota both exert SLO-specific effects for the various tissue-resident T cell subsets.

Aurélie Durand
Alexandra Audemard-Verger
Bruno Lucas
ResearchOpen Access04 Jan 2018
Nature Communications

Volume: 9, P: 1-12
Perinatal vitamin A excess impacts vitamin A and lipid metabolism in rat offspring

Angélique Berthomé
Tiffany Antoine
Emmanuelle Reboul
ResearchOpen Access07 Oct 2025
Scientific Reports

Volume: 15, P: 1-11
Learning, reflexivity, decision-making, and behavioral change for sustainable viticulture associated with participatory action research

Maxime Madouas
Mélanie Henaux
Jean Eugène Masson
ResearchOpen Access06 May 2023
Humanities and Social Sciences Communications

Volume: 10, P: 1-11
Multicentre phase II study of bifractionated CPT-11 with bimonthly leucovorin and 5-fluorouracil in patients with metastatic colorectal cancer pretreated with FOLFOX

F Recchia
G Saggio
S Rea
ResearchOpen Access05 Oct 2004
British Journal of Cancer

Volume: 91, P: 1442-1446
m⁶A RNA modification regulates innate lymphoid cell responses in a lineage-specific manner

Huang and colleagues show that METTL3-mediated m⁶A mRNA modifications support the transcriptional activity of activated ILC2s.

Yingyu Zhang
Wanwei Zhang
Yuefeng Huang
Research03 Jul 2023
Nature Immunology

Volume: 24, P: 1256-1264
PAR2 absence completely rescues inflammation and ichthyosis caused by altered CAP1/Prss8 expression in mouse skin

The activity of serine proteases, including CAP1/Prss8, is altered in some human skin disorders; however, the downstream effectors of these proteins are relatively unknown. Here, using animal models, the authors show that protease-activated receptor-2 is a critical component of the CAP1/Prss8 signalling cascade.

Simona Frateschi
Eric Camerer
Edith Hummler
ResearchOpen Access18 Jan 2011
Nature Communications

Volume: 2, P: 1-11
Transplantability in nude mice of embryonic and other childhood tumours

M F Rousseau-Merck
P Bigel
C Nezelof
Research01 Aug 1985
British Journal of Cancer

Volume: 52, P: 279-283
Leopard density and determinants of space use in a farming landscape in South Africa

McKaughan J.E.T.
Stephens P.A.
Hill R.A.
ResearchOpen Access08 May 2024
Scientific Reports

Volume: 14, P: 1-11
Osteosarcoma

T Philip
J Y Blay
P Thiesse
ResearchOpen Access01 May 2001
British Journal of Cancer

Volume: 84, P: 78-80
The deubiquitinating enzyme CYLD controls apical docking of basal bodies in ciliated epithelial cells

Mutations in the deubiquitinase gene CYLD are associated with cylindromatosis, a disease characterized by the development of skin appendage tumours. Eguether et al.discover that CYLD localizes to centrosomes and is required for basal body migration and docking, providing insight into its tumour suppressor activity.

Thibaut Eguether
Maria A. Ermolaeva
Anne-Marie Tassin
Research19 Aug 2014
Nature Communications

Volume: 5, P: 1-14
Cytokine response profiles of human myeloid factor-dependent leukemia cell lines

HG Drexler
M Zaborski
H Quentmeier
Research01 May 1997
Leukemia

Volume: 11, P: 701-708
A randomised phase II multicentre trial of irinotecan (CPT-11) using four different schedules in patients with metastatic colorectal cancer

N E Schoemaker
I E L M Kuppens
W W ten Bokkel Huinink
ResearchOpen Access21 Sept 2004
British Journal of Cancer

Volume: 91, P: 1434-1441
Transdisciplinary participatory-action-research from questions to actionable knowledge for sustainable viticulture development

Jean E. Masson
Isabelle Soustre-Gacougnolle
R. Lassablière
ResearchOpen Access25 Jan 2021
Humanities and Social Sciences Communications

Volume: 8, P: 1-9
Harnessing big ‘omics’ data and AI for drug discovery in hepatocellular carcinoma

Several big data ‘omics’ studies have analysed hepatocellular carcinoma (HCC). This Review describes omics studies in HCC and their potential in drug discovery and as candidate biomarkers. The application of emerging new artificial intelligence methods in HCC drug discovery is also discussed.

Bin Chen
Lana Garmire
Xin Chen
Reviews03 Jan 2020
Nature Reviews Gastroenterology & Hepatology

Volume: 17, P: 238-251
Intensified dose of cyclophosphamide with G-CSF support versus standard dose combined with platinum in first-line treatment of advanced ovarian cancer a randomised study from the GINECO group

I Ray-Coquard
D Paraiso
É Pujade-Lauraine
ResearchOpen Access09 Oct 2007
British Journal of Cancer

Volume: 97, P: 1200-1205
Frequency of extreme Sahelian storms tripled since 1982 in satellite observations

Since 1982, extreme daily rainfall in the western Sahel has increased persistently, owing to a warmer Sahara which has led to increased wind shear and an increase in intense storms.

Christopher M. Taylor
Danijel Belušić
Gérémy Panthou
Research27 Apr 2017
Nature

Volume: 544, P: 475-478
A phase II study of FOLFIRI-3 (double infusion of irinotecan combined with LV5FU) after FOLFOX in advanced colorectal cancer patients

M Mabro
P Artru
A de Gramont
ResearchOpen Access11 Apr 2006
British Journal of Cancer

Volume: 94, P: 1287-1292
Terminal megakaryocytic differentiation of TF-1 cells is induced by phorbol esters and thrombopoietin and is blocked by expression of PML/RARα fusion protein

U Testa
F Grignani
C Peschle
Research08 May 1998
Leukemia

Volume: 12, P: 563-570
High-dose mitoxantrone with peripheral blood progenitor cell rescue: toxicity, pharmacokinetics and implications for dosage and schedule

A Ballestrero
F Ferrando
F Patrone
Research01 Sept 1997
British Journal of Cancer

Volume: 76, P: 797-804

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