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Nature Structural & Molecular Biology (3)
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Showing 1–4 of 4 results

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NMD factors UPF2 and UPF3 bridge UPF1 to the exon junction complex and stimulate its RNA helicase activity

Hala Chamieh
Lionel Ballut
Hervé Le Hir
Research09 Dec 2007
Nature Structural & Molecular Biology

Volume: 15, P: 85-93
The structure of the Pan2–Pan3 core complex reveals cross-talk between deadenylase and pseudokinase

Conti and colleagues present the crystal structure of the yeast deadenylase Pan2–Pan3 core complex, revealing a 1:2 stoichiometry and indicating how deadenylase and pseudokinase domains work together to promote RNA deadenylation.

Ingmar B Schäfer
Michaela Rode
Elena Conti
Research01 Jun 2014
Nature Structural & Molecular Biology

Volume: 21, P: 591-598
InsP₆ binding to PIKK kinases revealed by the cryo-EM structure of an SMG1–SMG8–SMG9 complex

The structure of human SMG1–SMG8–SMG9, a PI(3)K-related protein kinase complex central to mRNA surveillance, uncovers an InsP₆-binding site in the SMG1 kinase that is conserved in mTOR and important for kinase activity.

Yair Gat
Jan Michael Schuller
Elena Conti
Research02 Dec 2019
Nature Structural & Molecular Biology

Volume: 26, P: 1089-1093
A large-scale mutation search reveals genetic heterogeneity in 3M syndrome

Céline Huber
Anee-Lise Delezoide
Valérie Cormier-Daire
Research29 Oct 2008
European Journal of Human Genetics

Volume: 17, P: 395-400