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Showing 1–3 of 3 results
Advanced filters: Author: Fabien Rideau Clear advanced filters
  • Arthroplasty is the main clinical option for the treatment of osteoarticular lesions, but has limited efficacy. Here, the authors use a wound dressing with autologous mesenchymal stromal cells, functionalised for local BMP2 delivery, and show feasibility and safety in standardised preclinical tests in animal models, suggesting suitability for use in clinical trials.

    • Laetitia Keller
    • Luc Pijnenburg
    • Nadia Benkirane-Jessel
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-10
  • The cell wall and cytoplasmic MreB polymers are important for bacterial cell shape. However, Spiroplasma cells lack a cell wall and still display a helical shape and kink-based motility, which is thought to rely on five MreB isoforms and a fibril protein. Here, Lartigue et al. show that heterologous expression of a single Spiroplasma MreB isoform confers helical shape and kinking ability to Mycoplasma cells, which are naturally spherical and non-motile.

    • Carole Lartigue
    • Bastien Lambert
    • Laure Béven
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-12