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Showing 1–3 of 3 results
Advanced filters: Author: Fabienne Gräbnitz Clear advanced filters

  • Asymmetrical cell division helps to maintain cellular heterogeneity in the T cell compartment. Here the authors examine the differential immune responses built by naive and virtual memory T cells from young and aged individuals, and explore the effect of mTOR inhibition on asymmetrical cell division and memory formation.

    • Mariana Borsa
    • Niculò Barandun
    • Annette Oxenius
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-12

  • CD40 agonists have been investigated as a strategy to awaken the immune system against cancers. Here, the authors use a virus encoding CD40L and tumour-associated antigens to enhance innate and adaptive immunity that together with tumour targeting antibodies controls the growth of tumours in mice.

    • José Medina-Echeverz
    • Maria Hinterberger
    • Henning Lauterbach
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-12

  • The spatial organization of cell surface receptors is critical for cell signaling and drug action. Here, the authors develop an optoproteomic method for mapping surface protein interactions, revealing cellular responses to antibodies, drugs and viral particles as well as immunosynapse signaling events.

    • Maik Müller
    • Fabienne Gräbnitz
    • Bernd Wollscheid
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-17