Direct reduction of unactivated alkyl halides for C(sp3)-N couplings under mild conditions presents a significant challenge in organic synthesis. Here the authors introduce an in situ formed pyridyl carbene-ligated copper (I) catalyst that is capable of abstracting halide atom and generating alkyl radicals for general C(sp3)-N couplings under visible light.
- Hang Luo
- Yupeng Yang
- Luqing Lin
