Nature Search

Rethinking and comprehensive planning of the floating city concept

A design focus on resilience, sustainability, and urban welfare can help the concept of floating cities to reach its potential for relieving land scarcity as well as demands on coastlines, suggests an analysis of space, food and energy requirements.

Carlo Ruzzo
Maria Luisa Cacurri
Felice Arena
ResearchOpen Access23 Jan 2026
Communications Earth & Environment

P: 1-13
Zika virus replicates in adult human brain tissue and impairs synapses and memory in mice

Here, using ex-vivo human adult cortical tissue and a mouse model, the authors investigate the functional consequences of Zika virus (ZIKV) infection in the adult brain, and show that ZIKV causes synapse damage and altered brain function that impacts cognition via activation of innate and inflammatory factors.

Claudia P. Figueiredo
Fernanda G. Q. Barros-Aragão
Sergio T. Ferreira
ResearchOpen Access05 Sept 2019
Nature Communications

Volume: 10, P: 1-16
Archaeogenetics reconstructs demography and extreme parental consanguinity in a Bronze Age community from Southern Italy

Ancient human DNA from Grotta della Monaca in reveals ancestry patterns, kinship-based burial practices, and evidence of a parent-offspring union in Bronze Age southern Italy.

Francesco Fontani
Felice Larocca
Alissa Mittnik
ResearchOpen Access15 Dec 2025
Communications Biology

Volume: 8, P: 1-12
The antioxidant N-acetylcysteine prevents cortical neuropathological phenotypes caused by adolescent Δ-9-tetrahydrocannabinol exposure in male rats

Hanna J. Szkudlarek
Rajkamalpreet Singh Mann
Steven R. Laviolette
ResearchOpen Access06 Oct 2025
Translational Psychiatry

Volume: 15, P: 1-16
Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer’s models

Expression of the exercise-induced myokine irisin (FNDC5) is lower in patients with AD. Whereas knockdown of FNDC5/irisin is sufficient to induce learning and memory deficits, restoration of its expression can ameliorate these phenotypes in rodent models.

Mychael V. Lourenco
Rudimar L. Frozza
Fernanda G. De Felice
Research07 Jan 2019
Nature Medicine

Volume: 25, P: 165-175
Italian research reorganization

MARCELLI G. CACACE
Correspondence11 Dec 1986
Nature

Volume: 324, P: 508
Polyunsaturated fatty-acids diet increases fear discrimination in rats and IGF-2 receptors signaling in the auditory cortex

Giulia Concina
Eugenio Manassero
Benedetto Sacchetti
ResearchOpen Access02 Jul 2025
Scientific Reports

Volume: 15, P: 1-13
Adolescent Δ-9-tetrahydrocannabinol exposure induces differential acute and long-term neuronal and molecular disturbances in dorsal vs. ventral hippocampal subregions

Marta De Felice
Chaochao Chen
Steven R. Laviolette
Research19 Nov 2022
Neuropsychopharmacology

Volume: 48, P: 540-551
Defective regulation of the eIF2-eIF2B translational axis underlies depressive-like behavior in mice and correlates with major depressive disorder in humans

Alinny R. Isaac
Mariana G. Chauvet
Mychael V. Lourenco
ResearchOpen Access01 Oct 2024
Translational Psychiatry

Volume: 14, P: 1-8
Neonatal infection leads to increased susceptibility to Aβ oligomer-induced brain inflammation, synapse loss and cognitive impairment in mice

Paula S. Frost
Fernanda Barros-Aragão
Julia R. Clarke
ResearchOpen Access11 Apr 2019
Cell Death & Disease

Volume: 10, P: 1-13
Serotonin depletion causes valproate-responsive manic-like condition and increased hippocampal neuroplasticity that are reversed by stress

Giacomo Maddaloni
Sara Migliarini
Massimo Pasqualetti
ResearchOpen Access07 Aug 2018
Scientific Reports

Volume: 8, P: 1-14
Pro-inflammatory interleukin-6 signaling links cognitive impairments and peripheral metabolic alterations in Alzheimer’s disease

Natalia M. Lyra e Silva
Rafaella A. Gonçalves
Fernanda G. De Felice
ResearchOpen Access28 Apr 2021
Translational Psychiatry

Volume: 11, P: 1-15
Synaptic proteasome is inhibited in Alzheimer’s disease models and associates with memory impairment in mice

A study involving several research models suggests that the function and synaptic localization of proteasomes, intracellular machineries involved in protein degradation, are impaired in the brains affected by Alzheimer’s disease.

Felipe C. Ribeiro
Danielle Cozachenco
Sergio T. Ferreira
ResearchOpen Access07 Nov 2023
Communications Biology

Volume: 6, P: 1-12
Short-chain fatty acids promote the effect of environmental signals on the gut microbiome and metabolome in mice

Mice exposed to environmental enrichment for 5 weeks display distinct microbiota composition and behavioral and metabolic profiles compared to mice exposed to a standard environment. Mice treated with a mixture of short-chain fatty acids that are produced by gut bacteria recapitulate some of the effects of this environmental enrichment.

Francesco Marrocco
Mary Delli Carpini
Cristina Limatola
ResearchOpen Access31 May 2022
Communications Biology

Volume: 5, P: 1-13
Diagnostic accuracy of liver stiffness measurement for the diagnosis of veno-occlusive disease/sinusoidal obstruction syndrome after hematopoietic stem cell transplantation (HSCT), the ELASTOVOD STUDY: an investigator-initiated, prospective, multicentre diagnostic clinical trial

Federico Ravaioli
Antonio Colecchia
Francesca Bonifazi
Research19 Apr 2025
Bone Marrow Transplantation

Volume: 60, P: 978-993

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