Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

View all journals
Search
Log in

nature
search

Search

Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Nature (1)
Nature Medicine (1)

Choose more journals

Article type Check one or more article types to show results from those article types only.

Research (2)

Subject Check one or more subjects to show results from those subjects only.

Cancer
Immunology
Medical research

Date Choose a date option to show results from those dates only.

Today
Last 7 days
Last 30 days
Last 12 months
Last 2 years
Last 5 years

Custom date range

Clear all filters

Sort by:

Relevance

Date published (new to old)

Date published (old to new)

Showing 1–2 of 2 results

Advanced filters: Author: Felix Quagliarello Clear advanced filters

T-cell invigoration to tumour burden ratio associated with anti-PD-1 response

The clinical benefit of anti-PD-1 antibody treatment is dependent on the extent to which exhausted CD8 T cells are reinvigorated in relation to the tumour burden of the patient.

Alexander C. Huang
Michael A. Postow
E. John Wherry
Research10 Apr 2017
Nature

Volume: 545, P: 60-65
A single dose of neoadjuvant PD-1 blockade predicts clinical outcomes in resectable melanoma

Neoadjuvant PD-1 blockade in patients with resectable melanoma followed by adjuvant maintenance results in early immunological effects driving clinical benefit and reveals transcriptional and genomic mechanisms of response.

Alexander C. Huang
Robert J. Orlowski
Tara C. Mitchell
Research25 Feb 2019
Nature Medicine

Volume: 25, P: 454-461

Search

Search articles by subject, keyword or author

Show results from

Advanced search

Quick links

Explore articles by subject
Find a job
Guide to authors
Editorial policies

Nature.com

nature.com sitemap

About Nature Portfolio

About us
Press releases
Press office
Contact us

Discover content

Journals A-Z
Articles by subject
protocols.io
Nature Index

Publishing policies

Nature portfolio policies
Open access

Author & Researcher services

Reprints & permissions
Research data
Language editing
Scientific editing
Nature Masterclasses
Research Solutions

Libraries & institutions

Librarian service & tools
Librarian portal
Open research
Recommend to library

Advertising & partnerships

Advertising
Partnerships & Services
Media kits
Branded content

Professional development

Nature Awards
Nature Careers
Nature Conferences

Regional websites

Nature Africa
Nature China
Nature India
Nature Japan
Nature Middle East

Privacy Policy
Use of cookies
Legal notice
Accessibility statement
Terms & Conditions
Your US state privacy rights

Search

Filter By:

T-cell invigoration to tumour burden ratio associated with anti-PD-1 response

A single dose of neoadjuvant PD-1 blockade predicts clinical outcomes in resectable melanoma

Search

Quick links