Coronary 'no-reflow' is a substantial clinical problem, even after successful percutaneous coronary intervention for myocardial infarction. In this Perspectives, article, O'Farrell and Attwell describe the similarities between this phenomenon and no-reflow in the brain after ischaemic stroke, and propose that pericytes contribute to the underlying pathophysiology in both situations. Cardiac pericytes might, therefore, be a novel therapeutic target for coronary no-reflow.
- Fergus M. O'Farrell
- David Attwell
