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Showing 1–7 of 7 results
Advanced filters: Author: Fernando Geu-Flores Clear advanced filters

  • White lupin is an annual crop cultivated for protein rich seeds and can produce cluster roots for efficient phosphate acquisition. Here, the authors generate high quality genome assemblies of a cultivated accession, a landrace, and a wild relative and provides insight into soil exploration and seed quality.

    • Bárbara Hufnagel
    • André Marques
    • Benjamin Péret
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-12

  • Although ginkgo terpenoids have been studied extensively for their pharmaceutical properties, knowledge on their biosynthesis remains limited. Here, the authors identify five multifunctional cytochrome P450s that catalyze the generation of the tert-butyl group and one of the lactone rings towards the biosynthesis of ginkgolides.

    • Victor Forman
    • Dan Luo
    • Irini Pateraki
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-14

  • Vicine and convicine are the main anti-nutritional factors restricting the consumption of faba bean. Transcript profiling combined with metabolite profiling was applied to identify a key enzyme responsible for the biosynthesis of vicine and convicine in faba bean.

    • Emilie Björnsdotter
    • Marcin Nadzieja
    • Fernando Geu-Flores
    Research
    Nature Plants
    Volume: 7, P: 923-931

  • The biosynthesis of iridoids, a class of bicyclic monoterpenes, features an atypical cyclization reaction catalyzed by iridoid synthase (ISY). Crystallographic and biochemical characterization of ISY from Catharanthus roseus provides insights into the ISY enzymatic mechanism and highlights similarities with the homologous progesterone 5β-reductase.

    • Hajo Kries
    • Lorenzo Caputi
    • Sarah E O'Connor
    Research
    Nature Chemical Biology
    Volume: 12, P: 6-8

  • Iridoids are a large family of bicyclic natural products that possess anticancer, anti-inflammatory, antifungal and antibacterial activities; here the essential cyclization step in their biosynthesis is identified, opening up the possibility of production of naturally occurring and synthetic variants of iridoids for use in pharmacy or agriculture.

    • Fernando Geu-Flores
    • Nathaniel H. Sherden
    • Sarah E. O’Connor
    Research
    Nature
    Volume: 492, P: 138-142