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Showing 1–4 of 4 results

Advanced filters: Author: Florent Carrette Clear advanced filters

Association of COVID-19 inflammation with activation of the C5a–C5aR1 axis

Blockade of the C5a–C5aR1 axis using anti-C5aR1 monoclonal antibodies prevented inflammation associated with COVID-19.

Julien Carvelli
Olivier Demaria
Eric Vivier
Research29 Jul 2020
Nature

Volume: 588, P: 146-150
Retraction Note: Tumor necrosis factor overcomes immune evasion in p53-mutant medulloblastoma

Alexandra Garancher
Hiromichi Suzuki
Robert J. Wechsler-Reya
Amendments and Corrections14 Dec 2021
Nature Neuroscience

Volume: 25, P: 127
RETRACTED ARTICLE: Tumor necrosis factor overcomes immune evasion in p53-mutant medulloblastoma

Medulloblastomas lacking p53 do not express surface class I major histocompatibility complex (MHC-I) and are resistant to immune rejection. Tumor necrosis factor rescues MHC-I expression and synergizes with immune checkpoint inhibitors to promote rejection.

Alexandra Garancher
Hiromichi Suzuki
Robert J. Wechsler-Reya
Research18 May 2020
Nature Neuroscience

Volume: 23, P: 842-853
Nuclear pore complex-mediated modulation of TCR signaling is required for naïve CD4⁺ T cell homeostasis

D’Angelo and colleagues show that the nucleoporin Nup210 plays a specific role in naïve CD4⁺ T cell homeostasis by regulating expression of Caveolin-2, which is required for tonic TCR signaling.

Joana Borlido
Stephen Sakuma
Maximiliano A. D’Angelo
Research07 May 2018
Nature Immunology

Volume: 19, P: 594-605