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Showing 1–7 of 7 results
Advanced filters: Author: Florian Praetorius Clear advanced filters
  • A fresh approach to protein design that incorporates excited intermediate states enables precise control over the lifetime of protein interactions, with potential applications in cell-signalling modulation and in biosensors and synthetic circuits.

    • Adam J. Broerman
    • Christoph Pollmann
    • David Baker
    ResearchOpen Access
    Nature
    Volume: 647, P: 528-535
  • We investigate the de novo design of allostery and suggest that it can arise from global coupling of the energetics of protein substructures without optimized allosteric communication pathways, providing a roadmap for the design of switchable molecular systems.

    • Arvind Pillai
    • Abbas Idris
    • David Baker
    ResearchOpen Access
    Nature
    Volume: 632, P: 911-920
  • The Yersinia YaxAB system is a pore-forming toxin of so far unknown structure. Here authors present X-ray and cryo-EM to structures of individual subunits and of the YaxAB pore complex, and find that YaxA binds to membranes first and recruits YaxB for subsequent oligomerization.

    • Bastian Bräuning
    • Eva Bertosin
    • Michael Groll
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-14
  • DNA origami allows the design of rod-shaped particles with specific geometrical features. This is exploited to examine how particle-level characteristics affect properties of the bulk phase and the superstructures such colloids assemble into.

    • Mahsa Siavashpouri
    • Christian H. Wachauf
    • Zvonimir Dogic
    Research
    Nature Materials
    Volume: 16, P: 849-856
  • All necessary strands for DNA origami can be created in a single scalable process by using bacteriophages to generate single-stranded precursor DNA containing the target sequences interleaved with self-excising DNA enzymes.

    • Florian Praetorius
    • Benjamin Kick
    • Hendrik Dietz
    Research
    Nature
    Volume: 552, P: 84-87