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Showing 1–6 of 6 results

Advanced filters: Author: Florian Röhrig Clear advanced filters

Targeting aldolase A in hepatocellular carcinoma leads to imbalanced glycolysis and energy stress due to uncontrolled FBP accumulation

Snaebjornsson et al. explore a selective vulnerability in cancer elicited by targeting aldolase A, which causes energy imbalance and prevents further metabolic adaptations.

Marteinn T. Snaebjornsson
Philipp Poeller
Almut Schulze
ResearchOpen Access20 Jan 2025
Nature Metabolism

Volume: 7, P: 348-366
Swarm Learning for decentralized and confidential clinical machine learning

Swarm Learning is a decentralized machine learning approach that outperforms classifiers developed at individual sites for COVID-19 and other diseases while preserving confidentiality and privacy.

Stefanie Warnat-Herresthal
Hartmut Schultze
Joachim L. Schultze
ResearchOpen Access26 May 2021
Nature

Volume: 594, P: 265-270
Leveraging electronic medical records to evaluate a computerized decision support system for staphylococcus bacteremia

Julia Palm
Ssuhir Alaid
André Scherag
ResearchOpen Access28 Mar 2025
npj Digital Medicine

Volume: 8, P: 1-9
The multifaceted roles of fatty acid synthesis in cancer

Lipid metabolism, especially fatty acid (FA) synthesis, is essential for membrane biosynthesis, energy storage and the generation of signalling molecules. This Review explores how FA synthesis promotes tumorigenesis and tumour progression and might be targeted therapeutically.

Florian Röhrig
Almut Schulze
Reviews23 Sept 2016
Nature Reviews Cancer

Volume: 16, P: 732-749
Active steroid hormone synthesis renders adrenocortical cells highly susceptible to type II ferroptosis induction

Isabel Weigand
Jochen Schreiner
Matthias Kroiss
ResearchOpen Access17 Mar 2020
Cell Death & Disease

Volume: 11, P: 1-12
Inhibition of Lysyl Oxidases Improves Drug Diffusion and Increases Efficacy of Cytotoxic Treatment in 3D Tumor Models

Friedrich Schütze
Florian Röhrig
Erik Henke
ResearchOpen Access01 Dec 2015
Scientific Reports

Volume: 5, P: 1-13