Extracellular vesicles (EVs) comprise a wide range of bilayer membrane-enclosed nanovesicles secreted by nearly all cell types and present in all human body fluids. In dilated cardiomyopathy, which is a frequent cause of heart transplantation, unraveling the specific combinations of cargo proteins within the EVs that peripherally circulate in patients hold promising potential for biomarker discovery.
- Santiago Roura
- Ana Gámez-Valero
- Antoni Bayes-Genis