The study identifies the L704F mutation in Arabidopsis ABCG36 as a key factor that uncouples the export of the auxin precursor indole-3-butyric acid from the defense compound camalexin. It highlights L704 as a crucial residue in the extracellular gate that influences substrate identity and balances growth-defense trade-offs in the Brassicaceae family.
- Jian Xia
- Alexandra Siffert
- Markus M. Geisler