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Showing 1–4 of 4 results
Advanced filters: Author: Francesca Peccati Clear advanced filters

  • Non-covalent interactions are very diverse, and they are generally difficult to investigate through experimental methods. Here tailored metal–organic frameworks serve as a platform for the systematic generation of a variety of non-covalent interactions, which can be studied through the electric fields produced by the charges and dipoles involved in the interactions.

    • Zhe Ji
    • Srijit Mukherjee
    • Steven G. Boxer
    ResearchOpen Access
    Nature Chemistry
    P: 1-8

  • By enriching productive mutational paths, a Kemp eliminase that speeds up proton abstraction >108-fold was developed in only five evolution rounds. Recombining it with a variant differing by 29 substitutions revealed the underlying fitness landscape.

    • David Patsch
    • Thomas Schwander
    • Rebecca M. Buller
    ResearchOpen Access
    Nature Chemical Biology
    Volume: 20, P: 1662-1669

  • Anthocyanins are used in the food and cosmetic industries. Due to the insufficient production in alternative hosts, they are still isolated from plants. Now, this study suggests an important catalytic role of glutathione transferases for the efficient biosynthesis of these natural products.

    • Michael Eichenberger
    • Thomas Schwander
    • Rebecca M. Buller
    ResearchOpen Access
    Nature Catalysis
    Volume: 6, P: 927-938