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Showing 1–2 of 2 results
Advanced filters: Author: Francesco Starinieri Clear advanced filters
  • Lentiviral vectors are promising gene delivery vehicles to target hepatocytes in vivo, but restriction factors limit their efficiency. Here, the authors counteract many of these restrictions, amplifying lentiviral gene transfer into hepatocytes, strengthening its translational potential.

    • Cesare Canepari
    • Michela Milani
    • Alessio Cantore
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-17
  • Simoni et al. show that liver fibrosis has a negative impact on in vivo viral vector-mediated gene transfer to hepatocytes in chemically induced and genetic mouse models varying on the type and severity of the pre-existing fibrosis and vector used.

    • Chiara Simoni
    • Justine Nozi
    • Alessio Cantore
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-13