Nature Search

Changing facial phenotype in Cohen syndrome: towards clues for an earlier diagnosis

Salima El Chehadeh-Djebbar
Edward Blair
Laurence Faivre
Research28 Nov 2012
European Journal of Human Genetics

Volume: 21, P: 736-742
Cortical evidence accumulation for visual perception occurs irrespective of reports

Perception can occur in the absence of report. Here, the authors use intracranial recordings to show that sequential sampling of sensory evidence in the ventral visual cortex supports perception beyond report.

François Stockart
Ramla Msheik
Nathan Faivre
ResearchOpen Access26 Sept 2025
Nature Communications

Volume: 16, P: 1-18
Unstable Ribonucleic Acid Revealed by Pulse Labelling of Escherichia Coli

FRANCOIS GROS
H. HIATT
J. D. WATSON
Research13 May 1961
Nature

Volume: 190, P: 581-585
The macaque anterior cingulate cortex translates counterfactual choice value into actual behavioral change

Fouragnan et al. used neuroimaging and ultrasound neuromodution in non-human primates to demonstrate the causal role of the anterior cingulate cortex in translating counterfactual values in future choices.

Elsa F. Fouragnan
Bolton K. H. Chau
Matthew F. S. Rushworth
Research15 Apr 2019
Nature Neuroscience

Volume: 22, P: 797-808
Trust within human-machine collectives depends on the perceived consensus about cooperative norms

Humans and machines are increasingly participating in mixed collectives in which they can help or hinder each other. Here the authors show the way in which people treat machines differently than humans in a stylized society of beneficiaries, helpers, punishers, and trustors.

Kinga Makovi
Anahit Sargsyan
Talal Rahwan
ResearchOpen Access30 May 2023
Nature Communications

Volume: 14, P: 1-12
A benchmark of expert-level academic questions to assess AI capabilities

Humanity’s Last Exam, a multi-modal benchmark at the frontier of human knowledge, is designed to be an expert-level closed-ended academic benchmark with broad subject coverage.

Long Phan
Alice Gatti
Davide Scaramuzza
ResearchOpen Access28 Jan 2026
Nature

Volume: 649, P: 1139-1146
Interferon dependent immune memory during HSV-1 neuronal latency via increased H3K9me3 and restriction by ATRX

This study uncovers a mechanism for innate immune memory in neurons, demonstrated by a more silent epigenetic structure of the Herpes Simplex Virus genome, resulting in a deep form of latent infection that is restricted for reactivation of the virus.

Abigail L. Whitford
Gaelle Auguste
Anna. R. Cliffe
ResearchOpen Access01 Dec 2025
Nature Communications

Volume: 17, P: 1-13
A prospective trial for breast cancer diagnosis by canine odorology

Dog olfaction has been reported to detect different human diseases, including cancer. Here, the authors present a trial where two trained dogs are exposed to human sweat samples to identify breast cancer.

Anne Tardivon
Benoit Mesurolle
Isabelle Fromantin
ResearchOpen Access27 Nov 2025
Nature Communications

Volume: 16, P: 1-9
Genetic associations with human longevity at the APOE and ACE loci

François Schächter
Laurence Faure-Delanef
Daniel Cohen
Research01 Jan 1994
Nature Genetics

Volume: 6, P: 29-32
Baseline brain function in the preadolescents of the ABCD Study

This paper reports activation patterns for fMRI tasks assessing response inhibition, working memory and reward processing obtained at baseline in the longitudinal ABCD Study, providing a reference for research into adolescent brain development.

B. Chaarani
S. Hahn
H. P. Garavan
Research07 Jun 2021
Nature Neuroscience

Volume: 24, P: 1176-1186
First-line durvalumab and tremelimumab with chemotherapy in RAS-mutated metastatic colorectal cancer: a phase 1b/2 trial

Treatment with anti-PDL1 and anti-CTLA4 in combination with mFOLFOX6 chemotherapy for patients with treatment-naive microsatellite stable metastatic colorectal cancer is safe, shows encouraging progression-free survival and induces a tumor-specific immune response.

Marion Thibaudin
Jean-David Fumet
François Ghiringhelli
ResearchOpen Access10 Aug 2023
Nature Medicine

Volume: 29, P: 2087-2098
Relationship between preoperative supine radiographs and intraoperative coronal spinal alignment in thoracic adolescent idiopathic scoliosis

François Luc
David Pichard
Brice Ilharreborde
ResearchOpen Access09 Jan 2026
Scientific Reports

Volume: 16, P: 1-12
CREB3 gain of function variants protect against ALS

Cross-species transcriptomics on vulnerable neuronal populations unravels the transcription factor CREB3 and its regulatory network as resilience markers of ALS. Genetics and epidemiology further identify the protective rare variant CREB3R119G.

Salim Megat
Christine Marques
Caroline Rouaux
ResearchOpen Access26 Mar 2025
Nature Communications

Volume: 16, P: 1-17
High frequency of gene transfer after fusion between bacteria and eukaryotic cells

Minoo Rassoulzadegan
Bernard Binetruy
François Cuzin
Research21 Jan 1982
Nature

Volume: 295, P: 257-259
Multiscale and re-entrant surface analysis of multi jet fusion surfaces and the effect of postprocessing via sandblasting

Patryk Mietliński
François Berkmans
Michał Wieczorowski
ResearchOpen Access03 Dec 2025
Scientific Reports

Volume: 15, P: 1-26
Divergent creativity in humans and large language models

Antoine Bellemare-Pepin
François Lespinasse
Karim Jerbi
ResearchOpen Access21 Jan 2026
Scientific Reports

Volume: 16, P: 1-18
Sterilization and contraception increase lifespan across vertebrates

Data collected from zoos and aquariums worldwide show that hormonal contraception or permanent surgical sterilization in mammals increase life expectancy, with different mechanisms in males and females.

Michael Garratt
Malgorzata Lagisz
Shinichi Nakagawa
Research10 Dec 2025
Nature

Volume: 649, P: 1264-1272
Estrogen-related receptor gene expression associates with sex differences in cortical atrophy in isolated REM sleep behavior disorder

This study reveals that females with isolated REM sleep behavior disorder show less neurodegeneration than males. The least affected regions in females are regions that overexpress estrogen-related genes, suggesting potential sex-specific neuroprotection.

Marie Filiatrault
Violette Ayral
Shady Rahayel
ResearchOpen Access10 Oct 2025
Nature Communications

Volume: 16, P: 1-15
Temporal acuity of vision decreases with eccentricity in virtual reality and is associated with schizotypy

Francois R. Foerster
Anne Giersch
Axel Cleeremans
ResearchOpen Access01 Jul 2025
Scientific Reports

Volume: 15, P: 1-11
Human HLA gene segment isolated by hybridization with mouse H–2 cDNA probes

Bertrand R. Jordan
François Bregegere
Philippe Kourilsky
Research09 Apr 1981
Nature

Volume: 290, P: 521-523
Spatial but not temporal orienting of attention enhances the temporal acuity of human peripheral vision

Voluntary spatial attention—but not temporal attention—enhances the temporal resolution of vision under uncertainty, despite the deployment of a synergistic spatiotemporal mechanism of selective attention involving posterior oscillations.

Francois R. Foerster
A. Giersch
A. Cleeremans
ResearchOpen Access29 Jul 2025
Communications Psychology

Volume: 3, P: 1-12
Multiomic analysis of malignant pleural mesothelioma identifies molecular axes and specialized tumor profiles driving intertumor heterogeneity

Genomic, transcriptomic and epigenetic analyses of malignant pleural mesothelioma identify molecular axes and specialized tumor profiles underlying intertumoral heterogeneity.

Lise Mangiante
Nicolas Alcala
Lynnette Fernandez-Cuesta
ResearchOpen Access16 Mar 2023
Nature Genetics

Volume: 55, P: 607-618
Macrophages excite muscle spindles with glutamate to bolster locomotion

A population of macrophages with exclusive molecular and functional signatures in the muscle spindles express machinery for synthesizing and releasing glutamate, and a cellular component, the muscle spindle macrophages, directly regulates neural activity and muscle contraction.

Yuyang Yan
Nuria Antolin
Simone Di Giovanni
ResearchOpen Access04 Dec 2024
Nature

Volume: 637, P: 698-707
Mature tertiary lymphoid structures predict immune checkpoint inhibitor efficacy in solid tumors independently of PD-L1 expression

Italiano and colleagues demonstrate the utility of mature tertiary lymphoid structures to predict response to immunotherapy, with pathologic analysis in three independent patient cohorts spanning multiple tumor types.

Lucile Vanhersecke
Maxime Brunet
Antoine Italiano
Research12 Aug 2021
Nature Cancer

Volume: 2, P: 794-802
Obesity-associated changes in molecular biology of primary breast cancer

The association between obesity and breast cancer biology remains understudied in humans. Here, using a large retrospective data collection, the authors identify obesity associated changes in the genomic, transcriptomic profile, and the tumor microenvironment of primary untreated breast tumors.

Ha-Linh Nguyen
Tatjana Geukens
Christine Desmedt
ResearchOpen Access21 Jul 2023
Nature Communications

Volume: 14, P: 1-17
Deep learning-based phenotyping reclassifies combined hepatocellular-cholangiocarcinoma

Combined hepatocellular-cholangiocarcinomas (cHCC-CCA) are challenging to diagnose, as they exhibit features of hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICCA). Here, the authors use deep learning to re-classify cHCC-CCA tumours into HCC or ICCA based on histopathology images.

Julien Calderaro
Narmin Ghaffari Laleh
Jakob Nikolas Kather
ResearchOpen Access14 Dec 2023
Nature Communications

Volume: 14, P: 1-10
Heterogeneity of white matter hyperintensities in Alzheimer’s disease captured by multimodal neuroimaging

Antoine Garnier-Crussard
Brigitte Landeau
Gaël Chetelat
ResearchOpen Access03 Nov 2025
Scientific Reports

Volume: 15, P: 1-11
Report on three additional patients and genotype–phenotype correlation in SLC25A22-related disorders group

Camille Lemattre
Marion Imbert-Bouteille
David Geneviève
Research08 Jul 2019
European Journal of Human Genetics

Volume: 27, P: 1692-1700
Mitochondrial class II introns encode proteins related to the reverse transcriptases of retroviruses

François Michel
B. Franz Lang
Research01 Aug 1985
Nature

Volume: 316, P: 641-643
Effects of eight neuropsychiatric copy number variants on human brain structure

Claudia Modenato
Kuldeep Kumar
Sébastien Jacquemont
ResearchOpen Access20 Jul 2021
Translational Psychiatry

Volume: 11, P: 1-10
Bifurcation in brain dynamics reveals a signature of conscious processing independent of report

Current knowledge on the neural basis of consciousness mostly relies on situations where people report their perception. Here, the authors provide evidence for the idea that bifurcation in brain dynamics reflects conscious perception independent of report.

Claire Sergent
Martina Corazzol
Daniel Pressnitzer
ResearchOpen Access19 Feb 2021
Nature Communications

Volume: 12, P: 1-19
Downregulation of the FTO m⁶A RNA demethylase promotes EMT-mediated progression of epithelial tumors and sensitivity to Wnt inhibitors

Fuks and colleagues report that downregulation of the FTO m⁶A RNA demethylase activates the Wnt pathway, promoting EMT-mediated progression of epithelial tumors and conferring sensitivity to Wnt inhibitors.

Jana Jeschke
Evelyne Collignon
François Fuks
Research23 Jun 2021
Nature Cancer

Volume: 2, P: 611-628
Motion sickness susceptibility modulates the impact of electrical vestibular stimulation on postural control

Karina Moïn-Darbari
Daniel Paromov
François Champoux
ResearchOpen Access25 Jul 2025
Scientific Reports

Volume: 15, P: 1-7
Pictorial adaptation of the quality of recovery 15 scale and psychometric validation into a pediatric surgical population

Eric Noll
Vincent De Angelis
Julien Pottecher
ResearchOpen Access28 Aug 2023
Scientific Reports

Volume: 13, P: 1-6
Defective axonal transport in a transgenic mouse model of amyotrophic lateral sclerosis

Jean-François Collard
Francine Côté
Jean-Pierre Julien
Research04 May 1995
Nature

Volume: 375, P: 61-64
Integrated multi-omics analysis of oligodendroglial tumours identifies three subgroups of 1p/19q co-deleted gliomas

Oligodendroglial tumours are characterized into three different molecular subtypes. Here, the authors use genomic data to identify a further three subgroups of 1p/19q co-deleted tumours and demonstrate an association with an aggressive phenotype.

Aurélie Kamoun
Ahmed Idbaih
Chiara Villa
ResearchOpen Access19 Apr 2016
Nature Communications

Volume: 7, P: 1-11
Diminishing benefits of urban living for children and adolescents’ growth and development

The advantage of living in cities compared with rural areas with respect to height and BMI in children and adolescents has generally become smaller globally from 1990 to 2020, except in sub-Saharan Africa.

Anu Mishra
Bin Zhou
Majid Ezzati
ResearchOpen Access29 Mar 2023
Nature

Volume: 615, P: 874-883
Quality of life and home enteral tube feeding: a French prospective study in patients with head and neck or oesophageal cancer

C Roberge
M Tran
M Henry-Amar
ResearchOpen Access17 Dec 1999
British Journal of Cancer

Volume: 82, P: 263-269
Plant conversions and abatement technologies cannot prevent stranding of power plant assets in 2 °C scenarios

Many existing and in-the-pipeline fossil-fuel power plants will have to be decommissioned or underused to avoid climate change beyond 2 °C, even under optimistic technology assumptions and after accounting for emission-reducing conversions.

Yangsiyu Lu
Francois Cohen
Alexander Pfeiffer
ResearchOpen Access10 Feb 2022
Nature Communications

Volume: 13, P: 1-11
Adaptive responses of animals to climate change are most likely insufficient

It is unclear whether species’ responses to climate change tend to be adaptive or sufficient to keep up with climate change. Here, Radchuk et al. perform a meta-analysis showing that in birds phenology has advanced adaptively in some species, though not all the way to the new optima.

Viktoriia Radchuk
Thomas Reed
Stephanie Kramer-Schadt
ResearchOpen Access23 Jul 2019
Nature Communications

Volume: 10, P: 1-14
Somatic mosaicism and common genetic variation contribute to the risk of very-early-onset inflammatory bowel disease

Adult forms of inflammatory bowel disease (IBD) are of a polygenic nature, but paediatric and very early onset (VEO) IBD also occur as monogenic forms. Here, using whole exome sequencing, the authors explore both the monogenic and polygenic contribution to VEO-IBD and characterize a rare somatic mosaic VEO-IBD patient.

Eva Gonçalves Serra
Tobias Schwerd
Carl A. Anderson
ResearchOpen Access21 Feb 2020
Nature Communications

Volume: 11, P: 1-15
A model of solar-cycle effects on palaeoclimate and its implications for the Elatina Formation

J.-Cl. Gérard
L. M. François
Research09 Apr 1987
Nature

Volume: 326, P: 577-580
Sympathetic regulation of cardiac calcium current is due exclusively to cAMP-dependent phosphorylation

H. Criss Hartzell
Pierre-Francois Méry
Gabor Szabo
Research13 Jun 1991
Nature

Volume: 351, P: 573-576
Transcriptome variation in human tissues revealed by long-read sequencing

To understand the contribution of variants to transcript expression regulation, long-read transcriptome data are generated from the GTEx resource, and a new software package to perform allele-specific analysis is developed.

Dafni A. Glinos
Garrett Garborcauskas
Beryl B. Cummings
Research03 Aug 2022
Nature

Volume: 608, P: 353-359
Static magnetic stimulation of the primary motor cortex impairs online but not offline motor sequence learning

Angélina Lacroix
Léa Proulx-Bégin
Jean-François Lepage
ResearchOpen Access08 Jul 2019
Scientific Reports

Volume: 9, P: 1-8
The inducible cytotoxic T-lymphocyte-associated gene transcript CTLA-1 sequence and gene localization to mouse chromosome 14

Jean-François Brunet
Magali Dosseto
Pierre Golstein
Research17 Jul 1986
Nature

Volume: 322, P: 268-271
TCF12 is mutated in anaplastic oligodendroglioma

Anaplastic oligodendrogliomas are rare and incurable primary brain tumours with few treatment options. Here Labrecheet al. perform whole-exome sequencing and identify recurring mutations in transcription factor TCF12, which are associated with aggressive tumours.

Karim Labreche
Iva Simeonova
Michel Wager
ResearchOpen Access12 Jun 2015
Nature Communications

Volume: 6, P: 1-9
Pharmacological targeting of glutamatergic neurons within the brainstem for weight reduction

Schneeberger et al. show that glutamatergic neurons within the dorsal raphe nucleus of the brainstem are enriched with the orexin 1 receptor Hcrtr1, which can be pharmacologically targeted to treat obesity in mice.

Marc Schneeberger
Nicola L. Brice
Jeffrey M. Friedman
ResearchOpen Access21 Nov 2022
Nature Metabolism

Volume: 4, P: 1495-1513
A new member of the immunoglobulin superfamily—CTLA-4

Jean-François Brunet
François Denizot
Pierre Golstein
Research16 Jul 1987
Nature

Volume: 328, P: 267-270
Ultrafast light targeting for high-throughput precise control of neuronal networks

Current holographic approaches for neuronal stimulation have limitations in their temporal resolution and the number of targeted neurons. Here, the authors demonstrate an approach for ultra-fast holographic light targeting which, combined with optogenetics, enables sub-millisecond control of sequential neuronal activation and high throughput simultaneous multicell illumination.

Giulia Faini
Dimitrii Tanese
Valentina Emiliani
ResearchOpen Access05 Apr 2023
Nature Communications

Volume: 14, P: 1-18

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