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Showing 1–2 of 2 results
Advanced filters: Author: Francois D’Hooge Clear advanced filters

  • Current methods for detection of tuberculosis rely mostly on bacterial culture from sputum. Here, the authors provide preclinical evidence that a positron-emitting mimic of the disaccharide trehalose ([18F]FDT) can be used as a radiotracer for the imaging of tuberculosis-associated lesions and monitoring the effects of treatment.

    • R. M. Naseer Khan
    • Yong-Mo Ahn
    • Benjamin G. Davis
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-19

  • The use of synthetic analogs to explore substrate promiscuity during trehalose incorporation into the mycobacterial cell wall yields a fluorescent probe that can be used to examine M. tuberculosis cell biology and detect this harmful pathogen within macrophages.

    • Keriann M Backus
    • Helena I Boshoff
    • Benjamin G Davis
    Research
    Nature Chemical Biology
    Volume: 7, P: 228-235