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Showing 1–2 of 2 results
Advanced filters: Author: Francois-Xavier Mauvais Clear advanced filters
  • Kinesin-1 is a motor protein transporting cargo along microtubules. Here the authors show that kinesin-1 is required for antigen cross-presentation and coordinates endosome scission from early endosomes to allow sorting internalized cargoes towards the recycling endosomal or lysosomal compartments.

    • Meriem Belabed
    • François-Xavier Mauvais
    • Gaël Ménasché
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-15
  • The receptor TLR9 needs to be carefully regulated to avoid recognition of self nucleic acids and ensuing autoinflammation. Saveanu and colleagues demonstrate a further level of regulation through the retention of TLR9 in IRAP+ endosomes.

    • Joel Babdor
    • Delphyne Descamps
    • Loredana Saveanu
    Research
    Nature Immunology
    Volume: 18, P: 509-518