Mildner and colleagues characterize two subsets (Cxcl10+ and Saa3+) of monocytes with pathogenic potential in the central nervous system of mice with experimentally induced autoimmune encephalomyelitis and show these pathogenic cells are not derived from Ly6C+ monocytes, but from early myeloid cell progenitors.
- Amir Giladi
- Lisa Katharina Wagner
- Alexander Mildner
