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Showing 1–9 of 9 results
Advanced filters: Author: Fred Etoc Clear advanced filters

  • Magneto-fluorescent nanoparticles hold promise for bioimaging applications, but synthesizing uniform particles with tunable sizes remains challenging. Chen et al. propose an approach for co-assembling magnetic particles with fluorescent quantum dots, leading to well-defined core-shell structures.

    • Ou Chen
    • Lars Riedemann
    • Moungi G. Bawendi
    Research
    Nature Communications
    Volume: 5, P: 1-8

  • Organizing centers act to pattern surrounding tissues during embryogenesis through the secretion of morphogens. Here the authors model human organizers using light stimulus to geometrically confine SHH expression in differentiating hESCs, generating spatially resolved proximal distal patterns.

    • Riccardo De Santis
    • Fred Etoc
    • Ali H. Brivanlou
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-11

  • Embryonic stem cells derived from the inner cell mass can differentiate to all embryonic lineages of any adult cell type and to a limited extent to extra-embryonic tissues. A study now allows the generation of pig and human stem cells with enhanced differentiation potential towards all embryonic and extra-embryonic fates, one step closer to the totipotent state of the fertilized egg.

    • Fred Etoc
    • Ali Brivanlou
    News & Views
    Nature Cell Biology
    Volume: 21, P: 671-673

  • This protocol describes how to differentiate and image human embryonic stem cells on micropatterned colonies to create radially organized domains of the germ layers mimicking embryonic gastrulation in vitro.

    • Alessia Deglincerti
    • Fred Etoc
    • Aryeh Warmflash
    Protocols
    Nature Protocols
    Volume: 11, P: 2223-2232

  • Simunovic et al. use human embryonic stem cells to generate a three-dimensional model of a human pre-gastrulation epiblast and show that anterior–posterior symmetry breaking can be induced by BMP4 and WNT signalling.

    • Mijo Simunovic
    • Jakob J. Metzger
    • Eric D. Siggia
    Research
    Nature Cell Biology
    Volume: 21, P: 900-910