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Nature Genetics (3)
Nature Reviews Immunology (2)
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Showing 1–7 of 7 results

Advanced filters: Author: Fred Ramsdell Clear advanced filters

Foxp3: a genetic foundation for regulatory T cell differentiation and function

Fred Ramsdell and Alexander Rudensky revisit the discovery of the Foxp3 gene and its foundational role in the differentiation and function of regulatory T cells.

Fred Ramsdell
Alexander Y. Rudensky
Comments & Opinion23 Jun 2020
Nature Immunology

Volume: 21, P: 708-709
An essential role for Scurfin in CD4⁺CD25⁺ T regulatory cells

Roli Khattri
Tom Cox
Fred Ramsdell
Research03 Mar 2003
Nature Immunology

Volume: 4, P: 337-342
X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy

Robert S. Wildin
Fred Ramsdell
Mary E. Brunkow
Research01 Jan 2001
Nature Genetics

Volume: 27, P: 18-20
The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

Craig L. Bennett
Jacinda Christie
Hans D. Ochs
Research01 Jan 2001
Nature Genetics

Volume: 27, P: 20-21
A forward-genetic approach for analysis of the immune system

Mark W. Appleby
Fred Ramsdell
Reviews01 Jun 2003
Nature Reviews Immunology

Volume: 3, P: 463-471
FOXP3 and scurfy: how it all began

The molecular cloning of the forkhead box P3 (FOXP3) gene led to a renaissance in the field of suppressor T cells (now known as regulatory T cells). In this Timeline article, the authors describe the key events that demonstrated the importance of FOXP3in immune regulation, starting with the discovery of the scurfy mouse some 65 years ago.

Fred Ramsdell
Steven F. Ziegler
Reviews11 Apr 2014
Nature Reviews Immunology

Volume: 14, P: 343-349
Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

Mary E. Brunkow
Eric W. Jeffery
Fred Ramsdell
Research01 Jan 2001
Nature Genetics

Volume: 27, P: 68-73