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Showing 1–8 of 8 results

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Author Correction: Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells

Brent D. G. Page
Nicholas C. K. Valerie
Thomas Helleday
Amendments and CorrectionsOpen Access01 Nov 2019
Nature Communications

Volume: 10, P: 1
Small-molecule inhibitors target Escherichia coli amyloid biogenesis and biofilm formation

Lynette Cegelski
Jerome S Pinkner
Scott J Hultgren
Research25 Oct 2009
Nature Chemical Biology

Volume: 5, P: 913-919
Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells

NUDIX hydrolases are an important family of nucleotide-metabolizing enzymes. Here, the authors identify potent, small molecule inhibitors of NUDT5, which is implicated in ADP-ribose and 8-oxo-guanine metabolism, and confirm its role in gene regulation and proliferation in breast cancer cells.

Brent D. G. Page
Nicholas C. K. Valerie
Thomas Helleday
ResearchOpen Access17 Jan 2018
Nature Communications

Volume: 9, P: 1-14
Structural basis for usher activation and intramolecular subunit transfer in P pilus biogenesis in Escherichia coli

The crystal structure of the PapC usher, together with the PapDG chaperone–subunit complex, helps to elucidate the molecular mechanisms by which individual pilus subunits are assembled into larger P pili.

Natalie S. Omattage
Zengqin Deng
Scott J. Hultgren
Research01 Oct 2018
Nature Microbiology

Volume: 3, P: 1362-1368
Single injection of small-molecule amyloid accelerator results in cell death of nigral dopamine neurons in mice

Maria Chermenina
Erik Chorell
Pernilla Wittung-Stafshede
ResearchOpen Access17 Dec 2015
npj Parkinson's Disease

Volume: 1, P: 1-9
Correction: Corrigendum: Direct Correlation Between Ligand-Induced α-Synuclein Oligomers and Amyloid-like Fibril Growth

Martin Nors Pedersen
Vito Foderà
Bente Vestergaard
Amendments and CorrectionsOpen Access28 Oct 2015
Scientific Reports

Volume: 5, P: 1
Mycobacterium tuberculosis Rv3160c is a TetR-like transcriptional repressor that regulates expression of the putative oxygenase Rv3161c

Hasan Tükenmez
Souvik Sarkar
Christer Larsson
ResearchOpen Access15 Jan 2021
Scientific Reports

Volume: 11, P: 1-10
Direct Correlation Between Ligand-Induced α-Synuclein Oligomers and Amyloid-like Fibril Growth

Martin Nors Pedersen
Vito Foderà
Bente Vestergaard
ResearchOpen Access28 May 2015
Scientific Reports

Volume: 5, P: 1-12