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Acta Pharmacologica Sinica (12)
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Showing 1–21 of 21 results

Advanced filters: Author: Fu-Ming Shen Clear advanced filters

Inhibition of STING pathway attenuates experimental abdominal aortic aneurysm progression

Yu-xin Chen
Chen-rui Shen
Hui Fu
Research10 Feb 2026
Acta Pharmacologica Sinica

P: 1-15
Synergistic effects of atenolol and amlodipine for lowering and stabilizing blood pressure in 2K1C renovascular hypertensive rats

Fu-ming Shen
He-hui Xie
Ding-feng Su
Research01 Nov 2005
Acta Pharmacologica Sinica

Volume: 26, P: 1303-1308
GSDME-dependent pyroptosis drives abdominal aortic aneurysm via promoting vascular senescence

Here they show that gasdermin-E (GSDME) acts as a key driver of abdominal aortic aneurysm (AAA) by triggering senescence in vascular smooth muscle cells, a process reversible with senolytic drugs, highlighting a promising therapeutic target of AAA.

Si-Jia Sun
Zhen Zhang
Pei Wang
ResearchOpen Access17 Dec 2025
Nature Communications

Volume: 16, P: 1-19
Synergism of hydrochlorothiazide and nitrendipine on reduction of blood pressure and blood pressure variability in spontaneously hypertensive rats

Ping Han
Zheng-xu Chu
Ding-feng Su
Research01 Dec 2006
Acta Pharmacologica Sinica

Volume: 27, P: 1575-1579
Effects of combination therapy with atenolol and amlodipine on blood pressure control and stroke prevention in stroke-prone spontaneously hypertensive rats

Gang Ling
Ai-jun Liu
Ding-feng Su
Research01 Nov 2007
Acta Pharmacologica Sinica

Volume: 28, P: 1755-1760
Synergism of Hydrochlorothiazide and Nifedipine on Blood Pressure Variability Reduction and Organ Protection in Spontaneously Hypertensive Rats

He-Hui Xie
Xiao-Fei Zhang
Ding-Feng Su
Research01 Apr 2008
Hypertension Research

Volume: 31, P: 685-691
Blood pressure, baroreflex sensitivity, and end organ damage in hybrid offspring of spontaneously hypertensive rats and Sprague-Dawley rats

He-hui Xie
Fu-ming Shen
Ding-feng Su
Research01 Sept 2005
Acta Pharmacologica Sinica

Volume: 26, P: 1049-1056
Effects of nine antihypertensive drugs on blood pressure variability in sinoaortic-denervated rats

Jin Wang
Fu-ming Shen
Ding-feng Su
Research01 Aug 2006
Acta Pharmacologica Sinica

Volume: 27, P: 1013-1017
Arterial baroreflex function does not influence telomere length in kidney of rats

Xiao-fei Zhang
Rui-fang Yang
Ding-feng Su
Research01 Nov 2006
Acta Pharmacologica Sinica

Volume: 27, P: 1409-1416
Gasdermin-E-mediated pyroptosis drives immune checkpoint inhibitor-associated myocarditis via cGAS-STING activation

ICI-induced myocarditis is fatal, but its mechanism is unclear. Here, the authors identify GSDME as a key driver by promoting cGAS-STING signaling, enhancing our understanding of its pathogenesis.

Si-Jia Sun
Xiao-Dong Jiao
Pei Wang
ResearchOpen Access05 Aug 2024
Nature Communications

Volume: 15, P: 1-23
Author Correction: Pro-ferroptotic signaling promotes arterial aging via vascular smooth muscle cell senescence

Di-Yang Sun
Wen-Bin Wu
Pei Wang
Amendments and CorrectionsOpen Access14 Nov 2024
Nature Communications

Volume: 15, P: 1
Pro-ferroptotic signaling promotes arterial aging via vascular smooth muscle cell senescence

Ferroptosis is a novel form of regulated cell death associated with lipid oxidation. Here, the authors demonstrate that the proferroptosis signal is activated and drives vascular aging by inducing senescence in vascular smooth muscle cells.

Di-Yang Sun
Wen-Bin Wu
Pei Wang
ResearchOpen Access16 Feb 2024
Nature Communications

Volume: 15, P: 1-22
Role of vascular K_ATP channels in blood pressure variability after sinoaortic denervation in rats

Zhong-wei Yang
Dong-jie Li
Fu-ming Shen
Research04 Feb 2011
Acta Pharmacologica Sinica

Volume: 32, P: 194-200
Clonidine, moxonidine, folic acid, and mecobalamin improve baroreflex function in stroke-prone, spontaneously hypertensive rats

Xiu-juan Ma
Fu-ming Shen
Ding-feng Su
Research01 Oct 2007
Acta Pharmacologica Sinica

Volume: 28, P: 1550-1558
The susceptibility of ventricular arrhythmia to aconitine in conscious Lyon hypertensive rats

Min Li
Jin Wang
Ding-feng Su
Research01 Feb 2007
Acta Pharmacologica Sinica

Volume: 28, P: 211-215
Improved gut microbiota by selenium-enriched Bifidobacterium longum DD98 alleviates chemotherapy-induced intestinal mucositis via inhibiting the STING pathway

Yu-Shuang Qiu
Chen Ye
Fu-Ming Shen
ResearchOpen Access21 Jun 2025
npj Science of Food

Volume: 9, P: 1-14
GSDME promotes MASLD by regulating pyroptosis, Drp1 citrullination-dependent mitochondrial dynamic, and energy balance in intestine and liver

Jia-Hui Zhu
Shen-Xi Ouyang
Pei Wang
Research16 Jul 2024
Cell Death & Differentiation

Volume: 31, P: 1467-1486
Activating α7nAChR ameliorates abdominal aortic aneurysm through inhibiting pyroptosis mediated by NLRP3 inflammasome

Hui Fu
Qi-rui Shen
Fu-ming Shen
ResearchOpen Access25 Feb 2022
Acta Pharmacologica Sinica

Volume: 43, P: 2585-2595
Ferroptosis inhibitor liproxstatin-1 alleviates metabolic dysfunction-associated fatty liver disease in mice: potential involvement of PANoptosis

Jie Tong
Xiu-ting Lan
Dong-jie Li
Research02 Nov 2022
Acta Pharmacologica Sinica

Volume: 44, P: 1014-1028
Ferroptotic stress facilitates smooth muscle cell dedifferentiation in arterial remodelling by disrupting mitochondrial homeostasis

Qing-Xin Ji
Fei-Yan Zeng
Pei Wang
Research07 Dec 2022
Cell Death & Differentiation

Volume: 30, P: 457-474
Genome-scale profiling of circulating cell-free DNA signatures for early detection of hepatocellular carcinoma in cirrhotic patients

Lei Chen
Ghassan K. Abou-Alfa
Chuan-Xin Wang
Correspondence15 Feb 2021
Cell Research

Volume: 31, P: 589-592