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Advanced filters: Author: Fushen Guo Clear advanced filters

  • Overnutrition has been linked to increased risk of cancer. Here, the authors show that exceeding nutrients suppress Enoyl-CoA hydratase-1 (ECHS1) activity by inducing its acetylation resulting in accumulation of fatty acids and branched-chain amino acids and oncogenic mTOR activation.

    • Ya-Kun Zhang
    • Yuan-Yuan Qu
    • Wei Xu
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-16