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Advanced filters: Author: Fuyao Song Clear advanced filters

Cancer-derived exosomal miR-25-3p promotes pre-metastatic niche formation by inducing vascular permeability and angiogenesis

The mechanisms underlying pre-metastatic niche formation by cancer derived exosomes is unclear. Here they show that colorectal cancer (CRC) derived exosomal miR-25-3p promotes vascular leakiness and angiogenesis, CRC metastasis, and is upregulated in CRC pateints with metastasis, and suggest miR-25-3p as a biomarker for CRC metastasis.

Zhicheng Zeng
Yuling Li
Li Liang
ResearchOpen Access19 Dec 2018
Nature Communications

Volume: 9, P: 1-14
FBX8 promotes metastatic dormancy of colorectal cancer in liver

Xiaohui Zhu
Feifei Wang
Li Liang
ResearchOpen Access14 Aug 2020
Cell Death & Disease

Volume: 11, P: 1-15
KNK437 restricts the growth and metastasis of colorectal cancer via targeting DNAJA1/CDC45 axis

Shaoshan Yang
Xiaoli Ren
Li Liang
Research02 Sept 2019
Oncogene

Volume: 39, P: 249-261

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