Small-fiber neuropathy is a condition that has been underdiagnosed in the past, partly because small nerve fibers cannot be observed using routine neurophysiological tests. Skin biopsy is a safe, minimally invasive tool that can provide important diagnostic information on small nerve fibers, and in this article Lauria and Devigili discuss how this approach is being applied to the diagnosis and monitoring of peripheral neuropathies.
- Giuseppe Lauria
- Grazia Devigili